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Corydaline ((+) -corydaline) is an isoquinoline alkaloid extracted from Corydalis Yanhusuo. It is an inhibitor of AChE with IC50 of 226 µM. Corydaline is a μ-opioid receptor agonist (Ki = 1.23 µM) that inhibits the replication of enterovirus 71 (EV71) (IC50 = 25.23 µM). Corydaline has anti-angiogenesis, anti-allergy, gastric emptying and anti-nociception effects.
| Molecular Weight | 369.45 |
| Formula | C22H27NO4 |
| CAS Number | 518-69-4 |
| Solubility (25°C) | DMSO 25 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Ji Won Jung, et al. Gender differences in corydaline pharmacokinetics in rats
[4] Ping Zhang, et al. Progress for treating tachyarrhythmia by corydaline
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