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Sinomenine hydrochloride (Cucoline hydrochloride), an alkaloid derived from Sinomenium Acutum, is a blocker of NF-κB activation. Sinomenine is also a μ-opioid receptor activator.
| Molecular Weight | 365.85 |
| Formula | C19H24ClNO4 |
| CAS Number | 6080-33-7 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 4°C, dry, sealed |
| Related NF-κB Products |
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| DCZ5418
DCZ5418 is an inhibitor of TRIP13. |
| Ro 106-9920
Ro 106-9920 is a potent inhibitor of NF-kappaB. |
| MRS2693 trisodium
MRS2693 trisodium is a selective P2Y6 agonist with an EC50 value of 0.015 μM. |
| PTD-p65-P1 Peptide TFA
PTD-p65-P1 Peptide TFA is a potent, selective nuclear transcription factor NF-κB inhibitor and derives from the p65 subunit of NF-κB amino acid residues 271-282, which selectively inhibits NF-κB activation induced by various inflammatory stimulation, down-regulate NF-κB-mediated gene expression and up-regulate apoptosis. |
| Narlumosbart
Narlumosbart is a human IgG4ҡ monoclonal antibody (mAb) that targets Receptor Activating Factor for Nuclear Factor κB Ligand (RANKL) and can be used in studies related to Giant Cell Tumor of Bone (GCTB). |
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