Cat.No. | Name | Information |
---|---|---|
M4787 | Euphorbia-factor-L1 | Euphorbia Factor L1, a diterpenoid compound, can reduce the protein and mRNA levels of Bcl-2, PI3K, AKT and mTOR, and up-regulate the protein levels of Caspase-9 and Caspase-3. There was no effect on caspase-9 and caspase-3 protease. Euphorbia Factor L1 can induce autophagy and has anti-cancer, anti-adipogenesis, anti-osteoclast formation and multiple drug resistance regulation effects. |
M4786 | Aristolochic acid A | Aristolochic acid A (Aristolochic acid I; TR 1736) is the principal component of the plant extract Aristolochic Acids, found in Aristolochia and Asarum herbs. Aristolochic acid A significantly decreased activator protein 1 (AP-1) and NF-κB activity. Aristolochic acid A reduces the expression of bladder cancer-associated BLCAP gene in human cells. |
M4785 | Pteryxin | Pteryxin, coumarin in the leaves of Pteryxin, has anti-obesity effect. Pteryxin is an effective butyrylcholinesterase (BChE) inhibitor with IC50 value of 12.96 μg/ mL |
M4784 | Hordenine | Hordenine is an alkaloid found in plants that inhibits melanin production by inhibiting the production of cAMP. |
M4783 | Diosimin | Diosimin is a flavonoid glycoside found in citrus fruits, hyssop, and rosemary. |
M4782 | Bilirubin | Bilirubin is a yellow breakdown product of heme catabolism. |
M4781 | Homovanillic-acid | Homovanillic acid is a dopamine metabolite associated with aromatic amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and adiponectin reductase deficiency. |
M4780 | 4-Demethylepipodophyllotoxin | 4 '- Demethylepipodophyllotoxin (4' - DMEP) is an intermediate compounds, can inhibit microtubule assembly. |
M4778 | Apo-12’-lycopenal | Apo-12’-lycopenal |
M4777 | Pregnenolone | Pregnenolone (3β -hydroxy-5-pregnen-20-one) is a powerful neurosteroid, and is the major precursor of various steroids, including steroids. Pregnenolone is a specific signaling inhibitor of cannabinoid CB1 receptor. |
M4775 | Gambogic-acid | Gambogic Acid (beta-Guttiferrin) a Gambogic resin from the Garcinia Hanburyi tree. Gambogic Acid (beta-guttiferrin) inhibited bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and McL-1 with IC50 values of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, respectively. 1.06 μM and 0.79 μM. |
M4774 | 11-hydroxy-sugiol | 11-hydroxy-sugiol |
M4773 | Jatropholone-B | Jatropholone-B |
M4772 | Berberine-Sulfate | Berberine-Sulfate |
M4771 | Dihydroberberine | Dihydroberberine inhibited the human Ether-related gene (hERG) channel and significantly reduced the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine has anti-inflammatory, antiatherosclerotic, hylipidemic and antitumor activities. |
M4770 | Berberrubine chloride | Berberrubine chloride is an active metabolite of berberine, attenuates ulcerative colitis in mice model. |
M4769 | Genkwanin | Genkwanin (Genkwanin) is an O-methylated flavonoid with anti-inflammatory activity. |
M4768 | Pinocembrin | Pinocembrin is a novel histidine decarboxylase inhibitor with anti-allergic potential in vitro. |
M4767 | aurantiamide-acetate | Aurantiamide acetate is a selective and orally active cathepsin inhibitor isolated from Portulaca Oleracea L. Aurantiamide acetate has anti-inflammatory activity and can be used to study inflammatory diseases. |
M4766 | Adynerin | Adynerin is a natural steroid found in the oleander plant. |
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