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Natural Products

Cat.No.  Name Information
M4787 Euphorbia-factor-L1 Euphorbia Factor L1, a diterpenoid compound, can reduce the protein and mRNA levels of Bcl-2, PI3K, AKT and mTOR, and up-regulate the protein levels of Caspase-9 and Caspase-3. There was no effect on caspase-9 and caspase-3 protease. Euphorbia Factor L1 can induce autophagy and has anti-cancer, anti-adipogenesis, anti-osteoclast formation and multiple drug resistance regulation effects.
M4786 Aristolochic acid A Aristolochic acid A (Aristolochic acid I; TR 1736) is the principal component of the plant extract Aristolochic Acids, found in Aristolochia and Asarum herbs. Aristolochic acid A significantly decreased activator protein 1 (AP-1) and NF-κB activity. Aristolochic acid A reduces the expression of bladder cancer-associated BLCAP gene in human cells.
M4785 Pteryxin Pteryxin, coumarin in the leaves of Pteryxin, has anti-obesity effect. Pteryxin is an effective butyrylcholinesterase (BChE) inhibitor with IC50 value of 12.96 μg/ mL
M4784 Hordenine Hordenine is an alkaloid found in plants that inhibits melanin production by inhibiting the production of cAMP.
M4783 Diosimin Diosimin is a flavonoid glycoside found in citrus fruits, hyssop, and rosemary.
M4782 Bilirubin Bilirubin is a yellow breakdown product of heme catabolism.
M4781 Homovanillic-acid Homovanillic acid is a dopamine metabolite associated with aromatic amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and adiponectin reductase deficiency.
M4780 4-Demethylepipodophyllotoxin 4 '- Demethylepipodophyllotoxin (4' - DMEP) is an intermediate compounds, can inhibit microtubule assembly.
M4778 Apo-12’-lycopenal Apo-12’-lycopenal
M4777 Pregnenolone Pregnenolone (3β -hydroxy-5-pregnen-20-one) is a powerful neurosteroid, and is the major precursor of various steroids, including steroids. Pregnenolone is a specific signaling inhibitor of cannabinoid CB1 receptor.
M4775 Gambogic-acid Gambogic Acid (beta-Guttiferrin) a Gambogic resin from the Garcinia Hanburyi tree. Gambogic Acid (beta-guttiferrin) inhibited bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and McL-1 with IC50 values of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, respectively. 1.06 μM and 0.79 μM.
M4774 11-hydroxy-sugiol 11-hydroxy-sugiol
M4773 Jatropholone-B Jatropholone-B
M4772 Berberine-Sulfate Berberine-Sulfate
M4771 Dihydroberberine Dihydroberberine inhibited the human Ether-related gene (hERG) channel and significantly reduced the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine has anti-inflammatory, antiatherosclerotic, hylipidemic and antitumor activities.
M4770 Berberrubine chloride Berberrubine chloride is an active metabolite of berberine, attenuates ulcerative colitis in mice model.
M4769 Genkwanin Genkwanin (Genkwanin) is an O-methylated flavonoid with anti-inflammatory activity.
M4768 Pinocembrin Pinocembrin is a novel histidine decarboxylase inhibitor with anti-allergic potential in vitro.
M4767 aurantiamide-acetate Aurantiamide acetate is a selective and orally active cathepsin inhibitor isolated from Portulaca Oleracea L. Aurantiamide acetate has anti-inflammatory activity and can be used to study inflammatory diseases.
M4766 Adynerin Adynerin is a natural steroid found in the oleander plant.

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