Cat.No. | Name | Information |
---|---|---|
M5547 | Daidzein | Daidzein is an inactive analogue of genistein, a tyrosine kinase inhibitor and an estrogen receptor activator. |
M5515 | Vitamin D3 | Vitamin D3 (Cholecalciferol) is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM. *The compound is unstable in solutions, freshly prepared is recommended |
M5436 | Azelaic acid | Azelaic acid is an unsaturated fatty acid derived from plant seeds, which can also be derived from ozonolysis of oleic acid, and has antimicrobial and antioxidant activity. |
M5422 | Ascomycin | Ascomycin (FK520), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3. |
M5388 | Ademetionine | Ademetionine (S-adenosyl-l-methionine; SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain. |
M5372 | 6-Acetamidohexanoic acid | 6-Acetamidohexanoic acid is a pharmaceutical intermediate. |
M5224 | Fumagillin | Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. |
M5222 | Mertansine | Mertansine is a tubulin inhibitor,inhibits the assembly of microtubules by binding to tubulin, with a linker structure can create an antibody-drug conjugate (ADC). *The compound is unstable in solutions, freshly prepared is recommended |
M5220 | Piperlongumine | Piperlongumine, a natural alkaloid from Piper longum L., is also a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1. |
M5185 | Xanthohumol | Xanthohumol is an inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV). |
M5184 | Kuwanone H | Kuwanone H |
M5181 | Gancaonin P | Gancaonin P |
M5180 | Quercetin hydrate | Quercetin hydrate |
M5176 | Isowighteone | isowighteone |
M5174 | Icariin | Icariin is a flavonol glycoside. Icariin inhibited PDE5 and PDE4 activity with IC50 of 432 nM and 73.50 μM, respectively. Icariin is also a PPARα activator. Icariin can increase cardiovascular and cerebrovascular blood flow, promote hematopoiesis, immunity and bone metabolism. |
M5173 | 8-Prenylnaringenin | 8-Prenylnaringenin is a prenylflavonoid isolated from hop cones Humulus lupulus, with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. |
M5172 | 6-Prenylnaringenin | (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface. |
M5169 | Bavachinin | Bavachinin(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae;has potent anti-angiogenic activity. |
M5145 | Anisomycin | Anisomycin is a pyrrolidine antibiotic, which inhibits protein synthesis, and also act as a JNK activator. |
M5082 | α-Cyclodextrin | α-CD has a smaller cavity size than β-CD, so it is more suitable for inclusion of small molecules in inclusions, and applications that require high CD solubility. |
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