| Cat.No. | Name | Information |
|---|---|---|
| M16335 | Skimmin | Skimmin (Umbelliferone glucoside) is a major pharmacologically active and orally active molecule present in Hydrangea paniculata, a medical herb used in traditional Chinese medicine as an anti-inflammatory agent. Skimmin has renal protective activity. Skimmin reduces cardiac fibrosis as well as decreasing TNF-α, IL-6, IL1β, and TGFβ1 in cardiac tissues. |
| M16331 | Sphondin | Sphondin |
| M16328 | Glycyrol | Glycyrol (Neoglycyrol) is a natural active substances isolated from the natural product molecule licorice, which has unique physiological activities such as anti-microbial, anti-oxidant, anti-ultraviolet, etc. |
| M16324 | Suberosin | Suberosin |
| M16312 | Toddaculin | Toddaculin |
| M16308 | Chalepensin | Chalepensin, a furanocoumarin isolated from the rutaceae plant Ruta chalepensis L., is a selective CYP2A6 inhibitor. Chalepensin also inhibits human CYP1A1, CYP1A2, CYP2A13, CYP2C9, CYP2D6, CYP2E1, and CYP3A4. |
| M16307 | Isogosferol | Isogosferol is a potent anti-inflammatory agent. Isogosferol decreases LPS-stimulated NO and IL-1β expression. Isogosferol decreases the LPS-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2. |
| M16299 | Isomeranzin | Isomeranzin |
| M16296 | Inophyllum E | Inophyllum E |
| M16278 | 8-Hydroxybergapten | 8-Hydroxybergapten |
| M16238 | Dorsmanin A | Dorsmanin A is a prenylated flavonoid from the twigs of Dorstenia mannii. |
| M16235 | Helichrysetin | Helichrysetin |
| M16219 | 2'-Hydroxy-3',4',6'-trimethoxychalcone | 2'-Hydroxy-3',4',6'-trimethoxychalcone |
| M16213 | Frangulin B | Frangulin B |
| M16203 | Urea | Urea is an end product of protein metabolism in humans and mammals and a major organic nitrogen compound excreted by the animal body. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Can be used as a diuretic agent. |
| M16195 | Thymine | Thymine is one of the four bases of DNA that can be used as a target for 5-fluorouracil (5-FU) in animal cancer models with a Km value of 2.3 μM. |
| M16181 | Cadambine | Cadambine is a potent inhibitor of DNA Topoisomerase IB of Leishmania donovani (LdTOP1LS), isolated from Anthocephalus cadamba. |
| M16170 | Robustine | Robustine |
| M16160 | Stepharine | Stepharine is an natural alkaloid which directly interactes with TLR4 and binds to the TLR4/MD2 complex (TLR4 inhibitor). Stepharine possesses anti-aging, anti-viral and anti-hypertensive effects. |
| M16158 | Koenimbine | Koenimbine is a natural product isolated from Murraya koenigii. The IC50 values of koenimbine in HT-29 and SW48 was calculated to be 50 μg/ml based on the MTT assay. The IC50 value was 75 μg/ml in IEC-18 cells. |
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