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Natural Products

Cat.No.  Name Information
M5547 Daidzein Daidzein is an inactive analogue of genistein, a tyrosine kinase inhibitor and an estrogen receptor activator.
M5515 Vitamin D3 Vitamin D3 (Cholecalciferol) is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM. *The compound is unstable in solutions, freshly prepared is recommended
M5436 Azelaic acid Azelaic acid is an unsaturated fatty acid derived from plant seeds, which can also be derived from ozonolysis of oleic acid, and has antimicrobial and antioxidant activity.
M5422 Ascomycin Ascomycin (FK520), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3.
M5388 Ademetionine Ademetionine (S-adenosyl-l-methionine; SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain.
M5372 6-Acetamidohexanoic acid 6-Acetamidohexanoic acid is a pharmaceutical intermediate.
M5224 Fumagillin Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
M5222 Mertansine Mertansine is a tubulin inhibitor,inhibits the assembly of microtubules by binding to tubulin, with a linker structure can create an antibody-drug conjugate (ADC). *The compound is unstable in solutions, freshly prepared is recommended
M5220 Piperlongumine Piperlongumine, a natural alkaloid from Piper longum L., is also a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1.
M5185 Xanthohumol Xanthohumol is an inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
M5184 Kuwanone H Kuwanone H
M5181 Gancaonin P Gancaonin P
M5180 Quercetin hydrate Quercetin hydrate
M5176 Isowighteone isowighteone
M5174 Icariin Icariin is a flavonol glycoside. Icariin inhibited PDE5 and PDE4 activity with IC50 of 432 nM and 73.50 μM, respectively. Icariin is also a PPARα activator. Icariin can increase cardiovascular and cerebrovascular blood flow, promote hematopoiesis, immunity and bone metabolism.
M5173 8-Prenylnaringenin 8-Prenylnaringenin is a prenylflavonoid isolated from hop cones Humulus lupulus, with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis.
M5172 6-Prenylnaringenin (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface.
M5169 Bavachinin Bavachinin(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae;has potent anti-angiogenic activity.
M5145 Anisomycin Anisomycin is a pyrrolidine antibiotic, which inhibits protein synthesis, and also act as a JNK activator.
M5082 α-Cyclodextrin α-CD has a smaller cavity size than β-CD, so it is more suitable for inclusion of small molecules in inclusions, and applications that require high CD solubility.

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