| Cat.No. | Name | Information |
|---|---|---|
| M8600 | Urolithin B | Urolithin B is a natural product with antiproliferative and antioxidant activity. |
| M8521 | Farrerol | Farrerol is major bioactive component from Rhododendron dauricum L. |
| M8404 | Danshensu | Danshensu is an active component of Salvia miltiorrhiza (Danshen) that suppresses the formation of reactive oxygen species, inhibits platelet adhesion and aggregation, and protects myocardium against ischemia. |
| M8391 | Icaritin | Icaritin (Anhydroicaritin) is a flavonoid derivative of isoprene from Epimedium Genusis. It effectively inhibited the proliferation of K562 cells (IC50 8 µM) and primary CML cells (IC50 13.4 µM for CML-CP and 18 µM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3/AKT signaling and enhance osteogenesis. |
| M8173 | Salinomycin | Salinomycin is a carboxylic polyether ionophore with antibiotic and anti-cancer properties. |
| M8008 | Propyl gallate | Propyl gallate is an antioxidant that exhibits antimicrobial activity. |
| M7887 | α-Linolenic acid | An ω-3 fatty acid that serves as a precursor to eicosapentaenoic acid (EPA) but not docosahexaenoic acid. |
| M7872 | Kojic acid | Tyrosinase inhibitor. |
| M7790 | Emodin | Emodin is an anti-SARS-CoV compound that blocks the interaction between the SARS-coronavirus spike protein and angiotensin converting enzyme 2 (ACE2). Emodin inhibited casein kinase 2 (CK2) and 11β-HSD1. Emodin can also induce necrotic apoptosis of glioma U251 cells and inhibit U251 cell proliferation by targeting the TNF/RIPK1/RIPK3 signaling pathway. |
| M7728 | Cytochalasin D | Cytochalasin D (Zygosporin A) is a cytopermeable actin polymerization inhibitor derived from fungi, which inhibits g-actin -- Cofilin interaction by binding g-actin. Cytochalasin D can also inhibit the binding of Cofilin to F-actin, reduce the release of exosomes and induce YAP phosphorylation. |
| M7647 | Bryostatin 1 | Bryostatin 1 is a natural macrolide isolated from the moss bug Bugula neritina and a potent PKC modulator of central nervous system (CNS) permeability.Bryostatin 1 binds to the isolated Munc13-1 C1 domain and the full-length Munc13-1 protein with a Ki value of 8.07 and 0.45 nM, respectively, and has anticancer, anti-inflammatory and neuroprotective activities. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Ki values of 8.07 nM and 0.45 nM, respectively, and exhibits anticancer, anti-inflammatory, and neuroprotective activities. |
| M7597 | Abscisic acid | Abscisic Acid is a plant hormone and growth regulator that is involved in several physiological mechanisms including seed dormancy, leaf abscission, stomatal movement, and plant stress responses. |
| M7419 | Toyocamycin | Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin is a adenosine analog; antifungal antibiotic. |
| M7341 | Swainsonine | Swainsonine is a potent inhibitor of α-mannosidase II. Swainsonine induces apoptosis and cell cycle arrest at G2/M phase. |
| M7246 | Sanguinarine chloride | Sanguinarine chloride is a inhibitor of protein phosphatase 2C (PP2C). |
| M7185 | Radicicol | Radicicol is a hsp90 inhibitor. Antifungal antibiotic. |
| M7177 | Quinine hydrochloride | Quinine hydrochloride is the hydrochloride form of Quinine, an alkaloid extracted from the bark of the cinchona tree, with antimalarial and antitumor activities, and an IC50 value of 60 ng/mL against P. falciparum strains passou and 107.8 ng/mL against P. falciparum strain 3CD7, respectively, and an inhibitor of potassium channels. Quinine hydrochloride is also a potassium channel inhibitor that inhibits voltage pulse-induced MT mSlo3 (KCa5.1) channel +100 mV currents, with an IC50 value of 169 μM. In addition, Quinine hydrochloride binds to purine nucleoside phosphorylase (PfNP) and PfNP with low nanomolar affinity. nucleoside phosphorylase (PfPNP) with low nanomolar affinity. |
| M6903 | Leptomycin B | Leptomycin B (CI 940; LMB (LMB) is a protein exit nuclear transport inhibitor. Leptomycin deactivates CRM1/exportin 1 by covalent modification at cysteine residues. Leptomycin B is a potent antifungal antibiotic that blocks the eukaryotic cell cycle. |
| M6750 | Ginkgolic Acid | Ginkgolic Acid is a inhibits SUMOylation by binding E1. |
| M6452 | Apocynin | Apocynin is a nADPH-oxidase inhibitor. |
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