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Leptomycin B (CI 940; LMB (LMB) is a protein exit nuclear transport inhibitor. Leptomycin deactivates CRM1/exportin 1 by covalent modification at cysteine residues. Leptomycin B is a potent antifungal antibiotic that blocks the eukaryotic cell cycle.
| Molecular Weight | 540.74 |
| Formula | C33H48O6 |
| CAS Number | 87081-35-4 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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