| Cat.No. | Name | Information |
|---|---|---|
| M7185 | Radicicol | Radicicol is a hsp90 inhibitor. Antifungal antibiotic. |
| M7177 | Quinine hydrochloride | Quinine hydrochloride is the hydrochloride form of Quinine, an alkaloid extracted from the bark of the cinchona tree, with antimalarial and antitumor activities, and an IC50 value of 60 ng/mL against P. falciparum strains passou and 107.8 ng/mL against P. falciparum strain 3CD7, respectively, and an inhibitor of potassium channels. Quinine hydrochloride is also a potassium channel inhibitor that inhibits voltage pulse-induced MT mSlo3 (KCa5.1) channel +100 mV currents, with an IC50 value of 169 μM. In addition, Quinine hydrochloride binds to purine nucleoside phosphorylase (PfNP) and PfNP with low nanomolar affinity. nucleoside phosphorylase (PfPNP) with low nanomolar affinity. |
| M6903 | Leptomycin B | Leptomycin B (CI 940; LMB (LMB) is a protein exit nuclear transport inhibitor. Leptomycin deactivates CRM1/exportin 1 by covalent modification at cysteine residues. Leptomycin B is a potent antifungal antibiotic that blocks the eukaryotic cell cycle. |
| M6750 | Ginkgolic Acid | Ginkgolic Acid is a inhibits SUMOylation by binding E1. |
| M6452 | Apocynin | Apocynin is a nADPH-oxidase inhibitor. |
| M6451 | Apigenin | Apigenin is a competitive CYP2C9 inhibitor with a Ki of 2 μM. |
| M6444 | Andrographolide | Andrographolide is a NF-κB inhibitor that inhibits NF-κB activation by covalently modifying the cysteine residue of P50 in endothelial cells without affecting IκBα degradation or p50/ P65 nuclear translocation. Andrographolide has antiviral effects. |
| M6228 | Wilforine | Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in idiopathic pulmonary fibrosis. |
| M6131 | Pristinamycin | Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic. The pristinamycins exhibit a strong synergistic antibacterial activity against a wide range of Gram-positive and some Gram-negative bacteria, including methicillin- and vancomycin-resistant strains. |
| M6062 | DL-Xylose | DL-Xylose is a sugar first isolated from wood. |
| M6020 | Tobramycin | Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. |
| M6007 | Theophylline | Theophylline is a methylated xanthine derivative; competitive nonselective phosphodiesterase inhibitor and nonselective adenosine receptor antagonist. |
| M5963 | Sisomicin sulfate | Sisomicin sulfate is an aminoglycoside antibiotic, isolated from the fermentation broth of a new species of the genus Micromonospora. |
| M5945 | Salicylic acid | Salicylic acid is a beta hydroxy acid that occurs as a natural compound in plants which is an inhibitor of ethylene biosynthesis and cyclooxygenase activity. |
| M5885 | Polymyxin B sulphate | Polymyxin B is an antibiotic primarily used for resistant gram-negative infections. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. |
| M5881 | Piperine | Piperine, a natural alkaloid isolated from Piper nigrum L, inhibits P-glycoprotein and CYP3A4 activities with an IC50 value of 61.94±0.054 μg/mL in HeLa cell. |
| M5836 | Orotic acid (6-Carboxyuracil) | Orotic acid(6-Carboxyuracil) is a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. |
| M5828 | Octinoxate | Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage. It is also used to reduce the appearance of scars. |
| M5811 | Netilmicin Sulfate | Netilmicin Sulfate is an aminoglycoside antibiotic derived from actinomycetes that specifically binds to the 30S small subunit of the bacterial ribosome, interfering with bacterial protein synthesis, with excellent killing activity against gram-negative bacteria. |
| M5807 | Napabucasin (BBI608) | Napabucasin (BBI608) is a first-in-class, orally active inhibitor of Stat3 that blocks stem cell activity in cancer cells by targeting the signal transducer and activator of transcription 3 pathway. Napabucasin inhibits cell proliferation of U87MG tumor xenografts in mice. |
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