Cat.No. | Name | Information |
---|---|---|
M8890 | Forchlorfenuron | Forchlorfenuron is a plant growth regulator and cytokinin, it can be used to increase fruit size of fruits. Forchlorfenuron inhibits septins and exhibits anti-parasitic, anticancer, and anti-angiogenic activities. |
M8878 | Inositol Nicotinate | Inositol Nicotinate is a formulation of niacin, which is also called vitamin B3, an essential human nutrient. |
M8868 | Zerumbone | Zerumbone is a TRAIL-induced apoptosis potentiator. Zerumbone is a monocyclic sesquiterpene compound isolated from the rhizomes of Zingiber zerumbet Smith. Zerumbone potently inhibits the activation of Epstein-Barr virus with an IC50 of 0.14 mM. |
M8698 | Kurarinone | Kurarinone, a flavanone from Sophora flavescens roots, is a potent activator of the large-conductance calcium-activated potassium channel (BKCa channel). |
M8666 | Urolithin A | Urolithin A is a naturally occurring compound produced by the metabolism in the body of vegetable tannins (ellagic acid and ellagitannins) found in food. It is also a mitochondrial modulator, regulating mitochondrial function in hematopoietic stem cells, as well as restoring blood regeneration in aging hematopoietic stem cells. In addition, Urolithin A is a ligand for the Aromatic Hydrocarbon Receptor (AhR), which promotes the anti-tumor function of CD8+ cytotoxic T-lymphocytes (CTLs) in an AhR-independent manner. Moreover, Urolithin A directly binds to ERK1/2 kinase, enhances its activation, and subsequently phosphorylates and activates the autophagy initiation factor ULK1, thereby promoting autophagy. |
M8600 | Urolithin B | Urolithin B is a natural product with antiproliferative and antioxidant activity. |
M8521 | Farrerol | Farrerol is major bioactive component from Rhododendron dauricum L. |
M8404 | Danshensu | Danshensu is an active component of Salvia miltiorrhiza (Danshen) that suppresses the formation of reactive oxygen species, inhibits platelet adhesion and aggregation, and protects myocardium against ischemia. |
M8391 | Icaritin | Icaritin (Anhydroicaritin) is a flavonoid derivative of isoprene from Epimedium Genusis. It effectively inhibited the proliferation of K562 cells (IC50 8 µM) and primary CML cells (IC50 13.4 µM for CML-CP and 18 µM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3/AKT signaling and enhance osteogenesis. |
M8173 | Salinomycin | Salinomycin is a carboxylic polyether ionophore with antibiotic and anti-cancer properties. |
M8008 | Propyl gallate | An antioxidant that exhibits antimicrobial activity. |
M7887 | α-Linolenic acid | An ω-3 fatty acid that serves as a precursor to eicosapentaenoic acid (EPA) but not docosahexaenoic acid. |
M7872 | Kojic acid | Tyrosinase inhibitor. |
M7790 | Emodin | Emodin is an anti-SARS-CoV compound that blocks the interaction between the SARS-coronavirus spike protein and angiotensin converting enzyme 2 (ACE2). Emodin inhibited casein kinase 2 (CK2) and 11β-HSD1. Emodin can also induce necrotic apoptosis of glioma U251 cells and inhibit U251 cell proliferation by targeting the TNF/RIPK1/RIPK3 signaling pathway. |
M7728 | Cytochalasin D | Cytochalasin D (Zygosporin A) is a cytopermeable actin polymerization inhibitor derived from fungi, which inhibits g-actin -- Cofilin interaction by binding g-actin. Cytochalasin D can also inhibit the binding of Cofilin to F-actin, reduce the release of exosomes and induce YAP phosphorylation. |
M7647 | Bryostatin 1 | Bryostatin 1 is a natural macrolide isolated from the moss bug Bugula neritina and a potent PKC modulator of central nervous system (CNS) permeability.Bryostatin 1 binds to the isolated Munc13-1 C1 domain and the full-length Munc13-1 protein with a Ki value of 8.07 and 0.45 nM, respectively, and has anticancer, anti-inflammatory and neuroprotective activities. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Ki values of 8.07 nM and 0.45 nM, respectively, and exhibits anticancer, anti-inflammatory, and neuroprotective activities. |
M7597 | Abscisic acid | Abscisic Acid is a plant hormone and growth regulator that is involved in several physiological mechanisms including seed dormancy, leaf abscission, stomatal movement, and plant stress responses. |
M7419 | Toyocamycin | Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin is a adenosine analog; antifungal antibiotic. |
M7341 | Swainsonine | Swainsonine is a potent inhibitor of α-mannosidase II. Swainsonine induces apoptosis and cell cycle arrest at G2/M phase. |
M7246 | Sanguinarine chloride | Sanguinarine chloride is a inhibitor of protein phosphatase 2C (PP2C). |
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