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Oleanonic acid

Cat. No. M17784

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Oleanonic acid Structure
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50mg USD 60  USD60 In stock
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Biological Activity

Oleanonic acid (3-Oxooleanolic acid) is an orally available triterpene that has anti-inflammatory and insecticidal properties. In vitro, oleanonic acid can improve oxidative stress, autophagy defects, ferroptosis, mitochondrial damage, and endoplasmic reticulum stress induced by Amyloid-β, and in vivo, it can alleviate myocardial hypertrophy in rats.

Chemical Information
Molecular Weight 454.68
Formula C30H46O3
CAS Number 17990-42-0
Solubility (25°C) DMSO 45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Benjamin Kingsley Harley, et al. Biomed Pharmacother. Hypoglycaemic activity of Oleanonic acid, a 3-oxotriterpenoid isolated from Aidia Genipiflora (DC.) Dandy, involves inhibition of carbohydrate metabolic enzymes and promotion of glucose uptake

[2] Elmira F Khusnutdinova, et al. Antibiotics (Basel). Development of New Antimicrobial Oleanonic Acid Polyamine Conjugates

[3] Hui Gao, et al. Mol Cell Endocrinol. Oleanonic acid ameliorates pressure overload-induced cardiac hypertrophy in rats: The role of PKCζ-NF-κB pathway

[4] Lucie Borkova, et al. ChemMedChem. Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid

[5] E M Giner-Larza, et al. Eur J Pharmacol. Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity

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Keywords: Oleanonic acid supplier, Triterpenoids, inhibitors, activators

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