About 30 results found for searched term "PRO-F" (0.007 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1934 | Tacrolimus (FK506) | Autophagy |
| Fujimycin; FR900506; Prograf | ||
| Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a potent, clinically-useful immunosuppressant in the same molecular class as cyclosporin A and rapamycin. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M2088 | Ciproxifan maleate | Histamine Receptor |
| FUB 359 maleate | ||
| Ciproxifan is an orally bioavailable, extremely potent histamine H3 inverse agonist/antagonist. | ||
| M2200 | Ciprofibrate | PPAR |
| Win35833 | ||
| Ciprofibrate is a peroxisome proliferator-activated receptor α (PPARα) agonist. | ||
| M2495 | Carprofen | COX |
| Carprofen inhibits canine COX2 with IC50 of 0.03 mM. | ||
| M2522 | Ciproxifan | Histamine Receptor |
| FUB-359 | ||
| Ciproxifan is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes. | ||
| M2529 | Clofibric Acid (PCIB) | PPAR |
| 2-(4-Chlorophenoxy)-2-methylpropionic acid; Chlorofibrinic acid | ||
| Clofibric acid (PCIB, Chlorofibrinic acid), a lipid fiber modulator Clofibrate, Etofibrate and Etofyllinclofibrate active metabolites, is a PPARα excitant, has the effect of lowering blood lipid. Clofibric acid is also a herbicide. | ||
| M2959 | Proadifen hydrochloride | Cytochrome P450 (e.g. CYP17) |
| SKF 525-A HCl | ||
| Proadifen hydrochloride is an inhibitor of the cytochrome P450 enzyme that blocks the metabolism of certain types of compounds. | ||
| M2963 | Proflavine Hemisulfate | Antibiotic |
| Proflavin hemisulfate; 3,6-Diaminoacridine hemisulfate | ||
| Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands. | ||
| M3359 | Ibuprofen | COX |
| Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. | ||
| M3360 | Zaltoprofen | COX |
| CN100 | ||
| Zaltoprofen is an orally active COX inhibitor with IC50 values of 1.3 and 0.34 μM for COX-1 and COX-2, respectively, and possesses potent anti-inflammatory activity. | ||
| M3391 | Ketoprofen | COX |
| Ketoprofen is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively. | ||
| M3412 | Propafenone hydrochloride | Sodium Channel |
| Propafenone HCl is a sodium-channel blocker that also has a high affinity for β-receptors (IC50 = 32 nM). It blocks transient outward potassium current (Ito) and sustained delayed rectifier K+ current (Isus) with IC50 values of 4.9 μM and 8.6 μM, respectively.In addition, Propafenone inhibits the proliferation of esophageal cancer by inducing mitochondrial dysfunction and apoptosis. | ||
| M3554 | Fenoprofen Calcium | COX |
| Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent. | ||
| M11432 | Razuprotafib | Phosphatase |
| AKB-9778 | ||
| Razuprotafib (AKB-9778) is an effective selective inhibitor of VE-PTP (HPTPß) catalytic activity (IC50=17 pM). | ||
| M3825 | Pluronic F-127 | Cell Staining |
| Poloxamer 407; Polyethylene-polypropylene glycol; PF-127 | ||
| Pluronic F-127 was used for fluorescent labeling of blood vessels, astrocytes, and neurons. Pluronic F-127 is frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, etc. to improve their water solubility. | ||
| M4903 | Ciprofloxacin | Topoisomerase |
| Bay 09867 | ||
| Ciprofloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity, with MIC90 of 0.024-6 μM. | ||
| M5052 | Tenofovir Disoproxil Fumarate | HIV Protease |
| Tenofovir DF | ||
| Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral compounds, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination. | ||
| M5060 | Propentofylline | PDE |
| Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them. | ||
| M5293 | Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO) | Inhibitor Cocktails |
| Protease inhibitor cocktails are used in mammalian cell lysates or tissue extracts to increase protein stability. | ||
| M5352 | (R)-(-)-Ibuprofen | COX |
| (R)-Ibuprofen | ||
| (R)-Ibuprofen, a nonsteroidal anti-inflammatory, is the less active enantiomer of ibuprofen, an inhibitor of Cox-1 and Cox-2. | ||
| M5462 | Bisoprolol fumarate | Adrenergic Receptor |
| EMD33512 | ||
| Bisoprolol fumarate is a selective type β1 adrenergic receptor blocker. | ||
| M5643 | Fenoprofen Calcium hydrate | COX |
| Fenoprofen calcium salt dihydrate | ||
| Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID). | ||
| M5658 | Flurbiprofen | COX |
| dl-Flurbiprofen | ||
| Flurbiprofen is a phenylalkanic acid derivative, which is a non-steroidal anti-inflammatory compound (NSAIDs). | ||
| M5707 | Indoprofen | Immunology/Inflammation |
| (±)-Indoprofe | ||
| Indoprofen is a non-steroidal anti-inflammatory compound, provide insight into treatments for spinal muscular atrophies. | ||
| M5755 | Loxoprofen | COX |
| Koloxo, Loxoprofene, Loxoprofeno | ||
| Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group. | ||
| M5774 | Metaproterenol Sulfate | Adrenergic Receptor |
| Metaproterenol Sulfate(Orciprenaline Sulfate) is a direct acting sympathetic agonist. It is a β 2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. It also has anti-inflammatory activity. | ||
| M5893 | Pranoprofen | COX |
| Pyranoprofen | ||
| Pranoprofen is a non-steroidal COX inhibitor, used as an anti-inflammatory drug in ophthalmology. | ||
| M5911 | Pyriproxyfen | Autophagy |
| Pyriproxyfen is a juvenile hormone analog, preventing larvae from developing into adulthood and thus rendering them unable to reproduce. Pyriproxyfen is a pyridine-based pesticide which is found to be effective against a variety of arthropoda. | ||
| M5985 | Suprofen | COX |
| Suprofen is a dual COX-1/COX-2 inhibitor, used as a non-steroidal anti-inflammatory analgesic and antipyretic. | ||
| M6195 | Propofol | GABA Receptor |
| 2,6-Diisopropylphenol | ||
| Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties. | ||
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