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Pluronic F-127

Cat. No. M3825
Pluronic F-127 Structure
Synonym:

Poloxamer 407; Polyethylene-polypropylene glycol

Size Price Availability Quantity
500mg USD 45  USD45 In stock
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Quality Control
  • Current batch:
  • Purity Cell culture level
  • COA
  • MSDS
Biological Activity

Pluronic F-127 was used for fluorescent labeling of blood vessels, astrocytes, and neurons. Pluronic F-127 was used to coat a siliconized coverslip to hold an egg extract in a study. Pluronic F-127 was added to phosphate buffered saline (PBS), to lower unspecific cell and protein adhesion to a PDMS-based microfluidic device.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight
Formula
CAS Number 9003-11-6
Purity Cell culture level
Solubility DMSO
Water (Need warm to 40-50℃)
Storage RT, protect from light
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Keywords: Pluronic F-127, Poloxamer 407; Polyethylene-polypropylene glycol supplier, Fluorescent Dye, inhibitors

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