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WGA

Cat. No. M13385
WGA Structure
Size Price Availability Quantity
5mg USD 975  USD975 In stock
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Quality Control
Biological Activity

Wheat agglutinin (WGA) is isolated from wheat (Triticum vulgaris, Weat germ), WGA selectively binds to glycoproteins and glycolipids of n-acetylglucosamine (GlcNAc) and n-acetylneuraminine (sialic acid) residues.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight
Formula
CAS Number 96508-08-6
Purity
Solubility N/A
Storage -20°C
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