About 30 results found for searched term "PIT" (0.026 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1650 | Aprepitant | Neurokinin Receptor |
| MK-0869, L-754030, Emend | ||
| Aprepitant (Emend) is an antiemetic chemical compound that belongs to a class of compounds called substance P antagonists (SPA). | ||
| M1667 | Sapitinib (AZD8931) | EGFR/HER2 |
| AZD-8931 | ||
| AZD8931 (Sapitinib) is an equipotent, reversible inhibitor of Signaling by EGFR, ERBB2 (HER2), and ERBB3 with IC50 of 4, 3, 4 nM respectively. | ||
| M1727 | Apitolisib (GDC-0980) | PI3K |
| RG7422; GNE 390 | ||
| Apitolisib (GDC-0980; GNE 390; RG 7422) is a potent, highly selective, oral, dual inhibitor of class I PI3K and mTOR. | ||
| M1832 | Maropitant | Neurokinin Receptor |
| Maropitant (Cerenia) is a novel, selective neurokinin type-1 (NK1) receptor antagonist. | ||
| M2184 | Indirubin | GSK-3 |
| C.I.73200; Couroupitine B; Indigo red; Indigopurpurin | ||
| Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of ~75 nM and 0.19 μM. | ||
| M2555 | AWD 131-138 | GABA Receptor |
| Imepitoin | ||
| AWD 131-138 is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models. | ||
| M2712 | Fosaprepitant dimeglumine salt | Neurokinin Receptor |
| MK-0517 dimeglumine salt; L-758,298 dimeglumine salt | ||
| Fosaprepitant is a water-soluble phosphoryl procompound for Aprepitant which is a NK1 antagonist.*The compound is unstable in solutions, freshly prepared is recommended | ||
| M3380 | Pitavastatin Calcium | Autophagy |
| Pitavastatin hemicalcium; NK-104 | ||
| Pitavastatin Calcium is a new type of statin. | ||
| M3882 | Netupitant | Neurokinin Receptor |
| CHEBI441603, CID6451149, D05152 | ||
| Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity with Ki of 0.95 nM. | ||
| M1569 | Monohydroxy Netupitant | Neurokinin Receptor |
| Monohydroxy Netupitant is the metabolite of Netupitant, which is a highly selective NK1 receptor antagonist. | ||
| M4417 | 7-Epitaxol | Microtubule |
| 7-epi-Paclitaxel | ||
| 7-Epi-Taxol is the active metabolite of Taxol, which has similar effects to Taxol in inhibiting cell proliferation, microtubule dissociation and inducing microtubule polymerization. | ||
| M7142 | PIT 1 | Others |
| PIT 1 is a pIP 3 antagonist. Blocks PIP 3-PH interaction; inhibits Akt signaling. | ||
| M9019 | Rolapitant | Neurokinin Receptor |
| SCH 619734 | ||
| Rolapitant (SCH619734) is an orally bioavailable, centrally-acting, selective neurokinin 1 receptor (NK1-receptor) antagonist with a Ki of 0.66 nM. | ||
| M9185 | Serlopitant | Neurokinin Receptor |
| VPD-737; MK-0594 | ||
| Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist. | ||
| M10179 | Vesnarinone | PDE |
| OPC-8212; Piteranometozine; Arkin | ||
| Vesnarinone is a cardiotonic agent, mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity. | ||
| M10714 | Pitolisant | Histamine Receptor |
| Tiprolisant | ||
| Pitolisant is a potent and selective non-imidazole recombinant hentistamine H3 receptor reversed agonist,Ki 0.16 nM. | ||
| M13516 | Pitstop 2 | Others |
| Pitstop 2 is a clathrin inhibitor which inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. Pitstop 2 has the potential for anti-cancer research. | ||
| M13996 | Pitolisant hydrochloride | Histamine Receptor |
| Ciproxidine; BF 2649 | ||
| Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM). | ||
| M14157 | D-JNKI-1 | JNK |
| AM-111; XG-102; Brimapitide | ||
| D-JNKI-1 (AM-111) is a highly potent and cell-permeable peptide inhibitor of JNK. | ||
| M17492 | Epitulipinolide diepoxide | Sesquiterpenoids |
| Epitulipinolide diepoxide | ||
| M17733 | 2-Epitormentic acid | Triterpenoids |
| 2-Epitormentic acid | ||
| M17743 | 3-Epiturraeanthin | Triterpenoids |
| 3-Epiturraeanthin | ||
| M17813 | Epitaraxerol | Triterpenoids |
| Epitaraxerol | ||
| M18884 | Sciadopitysin | Others |
| Sciadopitysin | ||
| M19360 | Nepitrin | Others |
| Nepitrin, isolated from Scrophularia striata, possess significant anti-inflammatory and anti-arthritic activity. | ||
| M21899 | Befetupitant | Others |
| Befetupitant | ||
| M22349 | Fosaprepitant | Neurokinin Receptor |
| L-758298; MK-0517 | ||
| Fosaprepitant is a precursor compound to Aprepitant and a neurokinin-1 receptor (NK1) antagonist that can be used in studies related to nausea and vomiting. | ||
| M24736 | Rovalpituzumab | Notch |
| Rovalpituzumab is a humanized monoclonal antibody against delta-like protein 3 (DLL3). Rovalpituzumab can be used in the synthesis of antibody-drug conjugate (ADC), Rovalpituzumab Tesirine. Rovalpituzumab has activity against small cell lung cancer (SCLC). | ||
| M25066 | Apitegromab | Others |
| SRK-015 | ||
| Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy. | ||
| M28038 | Pitofenone hydrochloride | AChR/AChE |
| Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
