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7-Epitaxol

Cat. No. M4417

All AbMole products are for research use only, cannot be used for human consumption.

7-Epitaxol Structure
Synonym:

7-epi-Paclitaxel

Size Price Availability Quantity
5mg USD 55  USD55 In stock
10mg USD 90  USD90 In stock
20mg USD 140  USD140 In stock
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Quality Control & Documentation
Biological Activity

7-Epi-Taxol is the active metabolite of Taxol, which has similar effects to Taxol in inhibiting cell proliferation, microtubule dissociation and inducing microtubule polymerization.

Chemical Information
Molecular Weight 853.91
Formula C47H51NO14
CAS Number 105454-04-4
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] V Bharath Kumar, et al. 7-Epitaxol Induces Apoptosis and Autophagy in Head and Neck Squamous Cell Carcinoma through Inhibition of the ERK Pathway

[2] Yanjie Liu, et al. An effective method to produce 7-epitaxol from taxol in HCO 3

[3] Jianhua Li, et al. Microbial transformation of cephalomannine by Luteibacter sp

[4] I Royer, et al. Paclitaxel metabolites in human plasma and urine: identification of 6 alpha-hydroxytaxol, 7-epitaxol and taxol hydrolysis products using liquid chromatography/atmospheric-pressure chemical ionization mass spectrometry

[5] I Ringel, et al. Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium

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Keywords: 7-Epitaxol, 7-epi-Paclitaxel supplier, Microtubule, inhibitors, activators

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