About 30 results found for searched term "EP3" (0.023 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2007 | Romidepsin (FK228) | HDAC |
| FK228; ISTODAX; Depsipeptide; FR 901228; NSC 630176 | ||
| Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended | ||
| M2045 | CEP-32496 | Raf |
| RXDX-105; Agerafenib | ||
| CEP-32496 is a potent orally active BRAF inhibitor with IC50 of 14 nM. | ||
| M2064 | CEP-33779 | JAK |
| CEP33779 | ||
| CEP-33779 is a novel, orally active, selective JAK2 inhibitor with IC50 of 1.8 nM. | ||
| M3183 | Quinacrine dihydrochloride | Anti-infection |
| Mepacrine dihydrochloride; SN-390 | ||
| Quinacrine dihydrochloride is a non-selective MAO-A/B inhibitor. Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis. | ||
| M3274 | Pentagastrin | Cholecystokinin Receptor |
| Peptavlon; ICI-50123 | ||
| Pentagastrin (ICI-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally. | ||
| M3539 | Verteporfin (CL 318952) | YAP |
| CL 318952; BPD-MA | ||
| Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin (CL 318952) is a YAP inhibitor that disrupts YAP-TEAD interactions, and it is also an inhibitor of autophagy. | ||
| M1261 | NFAT Inhibitor-1 (VIVIT peptide) | NFAT |
| VIVIT peptide; NFAT Inhibitor; ABM-7733 | ||
| NFAT Inhibitor-1 (VIVIT peptide) is a cell-permeable peptide inhibitor of nuclear factor of activated Tcells (NFAT), it is superior at inhibiting calcineurin-mediated dephosphorylation of NFAT1, NFAT2, and NFAT4 in cell extracts. | ||
| M4209 | ECG | COX |
| ECG; Epicatechin gallate; (-)-Epicatechin 3-O-gallate | ||
| ECG | ||
| M4984 | CEP-37440 | ALK |
| CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma). | ||
| M6336 | 3-Deazaneplanocin A hydrochloride | Histone Methyltransferase |
| DZNep hydrochloride; NSC 617989 hydrochloride; 3-Deazaneplanocin hydrochloride | ||
| 3-Deazaneplanocin A hydrochloride（DZNep HCl） is a eZH2 histone methyltransferase inhibitor. | ||
| M7904 | Methiothepin mesylate salt | Others |
| Metitepine mesylate; Ro 8-6837 mesylate | ||
| Methiothepin mesylate salt is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors. | ||
| M7981 | Oxamflatin | Others |
| Metacept-3 | ||
| Histone deacetylase inhibitor; anti-cancer agent. | ||
| M8253 | Mifamurtide | Others |
| CGP-19835; MTP-PE; MTP-cephalin; CGP19835; L-MTP-PE; MLV19835 | ||
| Mifamurtide (Muramyl tripeptide phosphatidylethanolamine; MTP-cephalin; MTP-PE) is a synthetic, lipophilic analog of muramyl dipeptide. | ||
| M8616 | Neoseptin-3 | Others |
| Neoseptin-3 is a highly efficacious and specific agonist of the mouse TLR4 (mTLR4)/myeloid differentiation factor 2 (MD-2) complex. | ||
| M8928 | CEP-40783 | c-Met |
| RXDX-106 | ||
| CEP-40783 (RXDX-106) is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. | ||
| M9004 | WDR5-0103 | Histone Methyltransferase |
| WD-Repeat Protein 5-0103 | ||
| WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM), inhibiting the catalytic activity of the MLL core complex in vitro (IC50 = 39 µM). | ||
| M9071 | Amyloid beta-peptide(25-35) | Amyloid |
| Aβ25-35; β-Amyloid peptide(25-35) | ||
| Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells. | ||
| M9420 | GSK3326595 | PRMTs |
| EPZ015938; GSK-3326595 | ||
| GSK3326595 is a potent, reversible and selective protein arginine methyltransferase 5 (PRMT5) inhibitor with broad antiproliferative activity for studies related to lymphoma and leukemia. | ||
| M9567 | Leptin (116-130) mouse | Others |
| LEP(116-130) mouse | ||
| Leptin (116-130) mouse is a synthetic leptin peptide fragment. | ||
| M10059 | Prolactin-Releasing Peptide (1-31) (human) | Peptides |
| Prolactin-Releasing Peptide (1-31) (human) is a high affinity GPR10 ligand. | ||
| M10233 | ((Cys31,Nva34)-Neuropeptide Y (27-36))2 | Neuropeptide Receptor |
| BWX 46 | ||
| ((Cys31,Nva34)-Neuropeptide Y (27-36))2, also called BWX 46, is a neuropeptide Y (NPY) Y5 receptor selective agonist. | ||
| M10247 | Nesiritide acetate | Peptides |
| natriureticpeptide; BNP-32; 124584-08-3 | ||
| Nesiritide acetate is an agonist of natriuretic peptide receptors (NPRs), with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. | ||
| M10372 | Vazegepant hydrochloride | CGRP Receptor |
| Zavegepant, BHV-3500 hydrochloride | ||
| Vazegepant (BHV-3500) hydrochloride is a first-in-class, high affinity CGRP receptor antagonist (hCGRP Ki= 0.023 nM). Vazegepant hydrochloride may be useful in the effective treatment of lung inflammation associated with COVID-19. | ||
| M10489 | NEO2734 (EP31670) | Epigenetic Reader Domain |
| EP31670; NEO-2734 | ||
| NEO2734 (EP31670) is a novel, orally active and selective dual inhibitor of p300/CBP and BET bromodomain with IC50 of both <30 nM. | ||
| M10532 | Tazemetostat hydrobromide | Histone Methyltransferase |
| EPZ-6438 hydrobromide; Tazemetostat HBr | ||
| Tazemetostat (EPZ-6438) hydrobromide is a first-in-class potent, selective and orally available EZH2 inhibitor. | ||
| M11319 | GLP-1(7-36), amide TFA | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA | ||
| TFA is a major intestinal hormone that stimulates insulin secretion by pancreatic beta cells in response to glucose. | ||
| M11506 | Ovalbumin (323-339) (chicken, japanese quail) | Peptides |
| OVA (323-339);OVA Peptide 323-339 | ||
| OVA Peptide (323-339) is an MHC Class II (H-2B) restricted OVA Peptide epitope that binds to the L-A (D) region of Class II MHC protein. It is widely used to study the natural properties of Class II MHC peptide binding and the mechanism of T cell activation. It is also commonly used to study immune allergic reactions, including asthma and food allergies. | ||
| M25417 | Masofaniten | Androgen Receptor |
| Androgen receptor-IN-2; EPI-7386 | ||
| Masofaniten (Androgen receptor-IN-2) is a potent and orally active androgen receptor inhibitor. Masofaniten inhibits androgen binding to androgen receptor with IC50 of 535 nM in the androgen-induced PSA-Luciferase assay. | ||
| M13931 | Calcitonin Gene Related Peptide (CGRP) (83-119), rat TFA | CGRP Receptor |
| Calcitonin Gene Related Peptide (CGRP) (83-119), rat (TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor (CRLR). | ||
| M13968 | GLP-1(7-36), amide acetate | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate | ||
| GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells. | ||
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