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Quinacrine dihydrochloride

Cat. No. M3183

All AbMole products are for research use only, cannot be used for human consumption.

Quinacrine dihydrochloride Structure
Synonym:

Mepacrine dihydrochloride; SN-390

Size Price Availability Quantity
25mg USD 25 In stock
50mg USD 28 In stock
100mg USD 36 In stock
200mg USD 52 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Quinacrine dihydrochloride is an inhibitor of cPLA2, MAO-A and MAO-B. Quinacrine dihydrochloride is a non-specific PLA2 (phospholipase A2) inhibitor. Quinacrine dihydrochloride acts as an AChR (acetylcholine receptor) antagonist. Quinacrine dihydrochloride suppresses glibenclamide-sensitive K+-currents (IC50 = 4.4 μM).

Chemical Information
Molecular Weight 472.88
Formula C23H30ClN3O.2HCl
CAS Number 69-05-6
Solubility (25°C) DMSO 30 mg/mL
Water 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Clemence Delaye, et al. Access and use of quinacrine (mepacrine) in the treatment of resistant giardiasis

[2] Romain Rotival, et al. Determination of quinacrine dihydrochloride dihydrate stability and characterization of its degradants

[3] Aida M Cancel, et al. A one-year neonatal mouse carcinogenesis study of quinacrine dihydrochloride

[4] M J Van Beek, et al. Antimalarials

[5] J Zipper, et al. Quinacrine revised

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Keywords: Quinacrine dihydrochloride, Mepacrine dihydrochloride; SN-390 supplier, Anti-infection, inhibitors, activators

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