Free shipping on all orders over $ 500

Quinacrine dihydrochloride

Cat. No. M3183

All AbMole products are for research use only, cannot be used for human consumption.

Quinacrine dihydrochloride Structure
Synonym:

Mepacrine dihydrochloride; SN-390

Size Price Availability Quantity
25mg USD 25  USD25 In stock
50mg USD 35  USD35 In stock
100mg USD 45  USD45 In stock
200mg USD 65  USD65 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Quinacrine dihydrochloride is an inhibitor of cPLA2, MAO-A and MAO-B. Quinacrine dihydrochloride is a non-specific PLA2 (phospholipase A2) inhibitor. Quinacrine dihydrochloride acts as an AChR (acetylcholine receptor) antagonist. Quinacrine dihydrochloride suppresses glibenclamide-sensitive K+-currents (IC50 = 4.4 μM).

Chemical Information
Molecular Weight 472.88
Formula C23H30ClN3O.2HCl
CAS Number 69-05-6
Solubility (25°C) DMSO 30 mg/mL
Water 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Clemence Delaye, et al. Access and use of quinacrine (mepacrine) in the treatment of resistant giardiasis

[2] Romain Rotival, et al. Determination of quinacrine dihydrochloride dihydrate stability and characterization of its degradants

[3] Aida M Cancel, et al. A one-year neonatal mouse carcinogenesis study of quinacrine dihydrochloride

[4] M J Van Beek, et al. Antimalarials

[5] J Zipper, et al. Quinacrine revised

Related Anti-infection Products
Strictinin

Strictinin is a phenolic compound which has potential antiviral, antibacterial and laxative activities. Strictinin occurs by accelerating intestinal transit rather than enhancing gastric emptying, increasing food intake, or inducing diarrhea in rats.

Torcitabine

Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent. Torcitabine has the potential for chronic hepatitis B virus infection research. Torcitabine (2'-Deoxy-L-cytidine) shows greater inhibition of first strand than second strand DNA synthesis.

ABMA

ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite.

DDX3-IN-1

DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 values of 50 and 36 μM for HIV and HCV, respectively. DDX3-IN-1 has antiviral activity.

K22

K22 is an inhibitor of coronavirus RNA synthesis that specifically targets membrane-associated coronavirus RNA synthesis. K22 effectively blocks replication of multiple coronaviruses by inhibiting the critical step of viral replication complex anchoring to host cell membranes to form double-membrane vesicles (DMVs). K22 exhibits broad-spectrum antiviral activity against diverse coronaviruses.

  Catalog
Abmole Inhibitor Catalog




Keywords: Quinacrine dihydrochloride, Mepacrine dihydrochloride; SN-390 supplier, Anti-infection, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.