Free shipping on all orders over $ 500

 About 30 results found for searched term "E-64" (0.013 seconds)

Cat.No.  Name Target
M1859 RepSox (ALK5 Inhibitor II) ALK
RepSox; E-616452; SJN 2511
RepSox (ALK5 Inhibitor II) is a potent and ATP-competitive inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively).
M2187 ETP-46464 ATM/ATR
ETP-46464 is a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα and ATM with IC50 of 0.6, 14, 36, 170 and 545 nM, respectively.
M2280 Tamoxifen Citrate (ICI 46474) Estrogen Receptor
ICI 46474; Istubal; Nolvadex
Tamoxifen Citrate is an antagonist of the estrogen receptor by competitive inhibition of estrogen binding.
M2376 Aloxistatin Cathepsin
Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor.
M2381 AMD3465 hexahydrobromide(AMD3465 ) CXCR
GENZ-644494 hexahydrobromide
AMD3465 hexahydrobromide(AMD3465 ) is an effective CXCR4 antagonist that inhibits 12G5 mAb in SupT1 cells. The IC50 values of CXCL12AF647 and CXCR4 were 0.75 nM and 18 nM, respectively. AMD 3465 also effectively inhibited X4 HIV replication (IC50, 1-10 nM), but not R5 HIV replication.
M2659 E-64 Autophagy
E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain.
M2690 Ethoxzolamide Carbonic Anhydrase
Redupresin; L-643786; PNU-4191
Ethoxzolamide is an inhibitor of the metalloenzyme carbonic anhydrase, which inhibits hCA I, hCA II, hCA IV, hCA VI and hCA VII with Ki of 25 nM, 8 nM, 93 nM, 43 nM and 0.8 nM, respectively.
M2823 Loxistatin Acid(E-64C) Cathepsin
NSC 694279, EP 475
Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
M3362 Tolfenamic Acid COX
GEA 6414
Tolfenamic Acid is a COX-2 inhibitor, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1.
M3549 Orlistat FAS
Tetrahydrolipstatin; Ro-18-0647
Orlistat is an irreversible inhibitor of pancreatic and gastric lipases with IC50 of 122 ng/ml for PL from human duodenal juice.
M3761 TH-237A Others
meso-GS 164
TH-237A is a novel neuroprotective agent, which possess protective properties against β-amyloid (Aβ)-induced neurodegeneration associated with Alzheimer's disease.
M3780 XL647 EGFR/HER2
EXEL-7647, KD-019
XL647 is an extremely potent and selective inhibitor of EGFR phosphorylation (IC50 = 0.3 nM).
M3784 Genz-644282 Topoisomerase
Genz 644282 is a novel non-camptothecin topoisomerase I inhibitor with an IC50 value of 0.4 nM in human bone marrow CFU-GM assay.
M3882 Netupitant Neurokinin Receptor
CHEBI441603, CID6451149, D05152
Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity with Ki of 0.95 nM.
M4477 Costunlide Apoptosis
(+)-Costunolide; Costunolid; Costus lactone; NSC 106404
M5431 Atosiban Acetate Vasopressin Receptor
RW22164 acetate; RWJ22164 acetate
Atosiban (RW22164; Tractocile) Acetate is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor antagonist (VOTra). Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane.
M5437 Azimilide Potassium Channel
Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.
M5648 Floxuridine DNA/RNA Synthesis
Deoxyfluorouridine, FDUR, NSC 27640
Floxuridine (5-fluorouracil 2'-deoxyriboside) is a pyrimidine analogue that is also an antitumor metabolite of oncology. Floxuridine inhibits the Poly(ADP-Ribose) polymerase and induces DNA damage in vitro by activating ATM and ATR checkpoint signaling pathways. Floxuridine is an effective inhibitor of Staphylococcus aureus infection and can induce apoptosis. Floxuridine is resistant to HSV and CMV viruses.
M6704 EHT 1864 2HCl Ras
EHT 1864 is a potent inhibitor of Rac family GTPases. EHT 1864 directly binds and impairs the ability of this small GTPase to engage critical downstream effectors required for growth transformation. The Kd values are 40, 50, 60, and 230 nM for Rac1, Rac1b, Rac2 and Rac3, respectively.
IMX; Isobutylmethylxanthine; Methylisobutylxanthine; NSC165960; SC2964
IBMX is a pDE inhibitor (non-selective) with IC50 values of 6.5±1.2, 26.3±3.9 and 31.7±5.3 μM for PDE3, 4 and 5 respectively.
M7249 SB 203580 hydrochloride p38 MAPK
Adezmapimod hydrochloride ; RWJ 64809 hydrochloride
SB 203580 hydrochloride is a selective inhibitor of p38 MAPK; water-soluble.
M8303 Azimilide dihydrochloride AChR/AChE
NE-10064 Dihydrochloride
Azimilide is an investigational class III anti-arrhythmic compound that blocks fast and slow components of the delayed rectifier cardiac potassium channels.
M8510 Cariporide Sodium Channel
Cariporide is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter.
M9006 NSC5844 CCR
NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties.
M9289 E6446 dihydrochloride TLR
E6446 2HCl; E-6446 hydrochloride
E6446 dihydrochloride is a synthetic antagonist of TLR7 and TLR9.
M9475 Sardomozide dihydrochloride Others
Sardomozide 2HCl; CGP 48664A
Sardomozide dihydrochloride (also known as SAM486A or CGP48664) is a second-generation polyamine synthesis inhibitor, which inhibits the activity of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (SAMDC).
M10427 OVA Peptide (257-264) TFA Peptides
OVA Peptide (257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
M10500 Remibrutinib (LOU064) BTK
Remibrutinib (LOU064) is a potentially best-in-class "best-in-class" orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM and an IC50 value of 0.23 μM for inhibition of BTK activity in blood. Remibrutinib can be used to study chronic urticaria (CU).
M10532 Tazemetostat hydrobromide Histone Methyltransferase
EPZ-6438 hydrobromide; Tazemetostat HBr
Tazemetostat (EPZ-6438) hydrobromide is a potent, selective and orally available EZH2 inhibitor.
M11279 GNE-6468 Others
Gne-6468 is a potent and selective RORγ (RORc) reverse agonist with an EC50 value of 2 nM. Gne-6468 inhibited IL-17 in PBMC with EC50 value of 30 nM.

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.