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NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties. NSC5844 shows 3-fold increased activity in MDA-MB-468 cells (GI50 = 7.35 μM), compared to Chloroquine. NSC5844 shows lower activity (GI50 = 14.80 M) in the MCF-7 cell line.
| Molecular Weight | 383.27 |
| Formula | C20H16Cl2N4 |
| CAS Number | 140926-75-6 |
| Solubility (25°C) | DMSO 10 mM |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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