Inhibitor/Activator
Cat.No. | Name | Information |
---|---|---|
M7224 | RS 504393 | RS 504393 is a highly selective CCR2 chemokine receptor antagonist. |
M40749 | CCR8 Antagonist 1 | CCR8 Antagonist 1 is a potent human CCR8 antagonist with a Ki value of 1.6 nM. |
M20858 | DAPTA | DAPTA is a water soluble potent, selective CCR5 inhibitor which potently inhibits specific CD4-dependent binding of gp120 Bal (IC50 = 0.06 nM) and CM235 (IC50 = 0.32 nM) to CCR5. |
M20822 | PF-4136309 | PF-4136309 (INCB8761, PF-04136309) is a potent, selective, and orally bioavailable CCR2 antagonist with an IC50 of 5.2 nM for human CCR2. |
M20778 | R243 | R243 is an inhibitor of Chemokine (C-C motif) receptor 8 (CCR8) signaling and chemotaxis. |
M14657 | AZD8797 | AZD8797 (KAND567) is an allosteric non-competitive and orally active antagonist of the human CX3CR1 receptor; antagonizes CX3CR1 and CXCR2 with Kis of 3.9 and 2800 nM, respectively. |
M13928 | CCR2 antagonist 4 | CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM. |
M13924 | CCR6 inhibitor 1 | CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). |
M13923 | CCR2-RA-[R] | CCR2-RA-[R] is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM. |
M13922 | BX471 hydrochloride | BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. |
M13921 | AZD2098 | AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research. |
M13920 | AZ084 | AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma. |
M11028 | RS102895 | RS102895 is a potent CCR2 antagonist,IC50 The value is 360 nM . |
M10190 | Cenicriviroc | Cenicriviroc, also known as TAK-652 and TBR-652, is an orally active, dual antagonist of CCR2/CCR5. |
M9944 | 7,4'-Dihydroxyflavone | 7,4'-Dihydroxyflavone, a flavonoid isolated from Glycyrrhiza uralensis, is an eotaxin/CCL11 inhibitor. |
M9884 | INCB3284 | INCB3284 is a potent, selective, and orally bioavailable hCCR2 antagonist, exhibited an IC50 of 3.7 nM in antagonism of monocyte chemoattractant protein-1 binding to hCCR2. |
M9444 | Cenicriviroc Mesylate | Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, and it also inhibits both HIV-1 and HIV-2. |
M9135 | TAK-779 | TAK-779 is a potent and selective nonpeptide antagonist of CCR5, with a Ki of 1.1 nM for CCR5. |
M9131 | ZK-756326 dihydrochloride | ZK-756326 dihydrochloride is a potent, selective and non-peptide CCR8 chemokine receptor agonist. |
M9006 | NSC5844 | NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties. |
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