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C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride (1 mg/kg; i.p.; daily; for 3 days) significantly less microgliosis in acute liver failure mice.
| Molecular Weight | 540.57 |
| Formula | C27H43Cl2N5O2 |
| CAS Number | 1784252-84-1 |
| Solubility (25°C) | Water 25 mg/mL DMSO 25 mg/mL |
| Storage | 4°C, dry, sealed |
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Products are for research use only. Not for human use. We do not sell to patients.
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