All AbMole products are for research use only, cannot be used for human consumption.
INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
| Molecular Weight | 577.59 |
| CAS Number | 1262238-11-8 |
| Solubility (25°C) | DMSO 150 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related CCR Products |
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| C-021 dihydrochloride
C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. |
| C-021
C-021 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. |
| AZD-5672
AZD-5672 is an orally active, potent, and selective CCR5 antagonist (IC50=0.32 nM). |
| MLN3126
MLN3126 is an orally active and potent CCR9 antagonist. |
| AZD2423
AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator. |
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Products are for research use only. Not for human use. We do not sell to patients.
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