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Loxistatin Acid

Cat. No. M2823

All AbMole products are for research use only, cannot be used for human consumption.

Loxistatin Acid Structure
Synonym:

E-64C; NSC 694279; EP 475

Size Price Availability Quantity
1mg USD 60  USD60 In stock
5mg USD 120  USD120 In stock
10mg USD 200  USD200 In stock
25mg USD 350  USD350 In stock
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Quality Control & Documentation
Biological Activity

Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.

Chemical Information
Molecular Weight 314.38
Formula C15H26N2O5
CAS Number 76684-89-4
Form Solid
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Florian Kleemiss, et al. Similarities and Differences between Crystal and Enzyme Environmental Effects on the Electron Density of Drug Molecules

[2] K Fukushima, et al. Identification of glutathione conjugate formed from loxistatin in rats

[3] K Fukushima, et al. An epoxysuccinic acid derivative(loxistatin)-induced hepatic injury in rats and hamsters

[4] K Fukushima, et al. Metabolic fate of loxistatin in rat

[5] H Kondo, et al. Inhibitory effect of oryzacystatins and a truncation mutant on the replication of poliovirus in infected Vero cells

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  Catalog
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Keywords: Loxistatin Acid, E-64C; NSC 694279; EP 475 supplier, Cathepsin, inhibitors, activators

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