Cathepsin Cathepsin

Inhibitors

Cat.No.	Name	Information
M5167	Calpeptin	Calpeptin is a potent, cell-permeable inhibitor of the Ca²⁺-dependent protease, calpain.
M9353	N-Ethylmaleimide	N-Ethylmaleimide (NEM) is a cysteine protease inhibitor.
M3636	Leupeptin hemisulfate	Leupeptin hemisulfate hemisulfate is the reversible inhibitor of lysosomal serine and cysteine proteinases; Leupeptin; inhibition of cathepsin B(Ki=6 nM), calpain(Ki=10 nM), trypsin (Ki=35 nM), plasmin (Ki=3.4 μM) and kallikrein (Ki=19 μM) had no effect on chymotrypsin, elastase, renin, or pepsin.
M21400	LHVS	LHVS is a potent, non-selective, irreversible, cell-permeable inhibitor of cysteine protease and cathepsin. lHVS reduces actin ring formation. lHVS inhibits T. gondii invasion with an IC50 of 10 μM.
M14309	Z-LVG-CHN2	Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase.
M14308	SID 26681509 quarterhydrate	SID 26681509 quarterhydrate is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC₅₀ of 56 nM.
M14307	LY 3000328	LY 3000328 is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively.
M14306	Cysteine Protease inhibitor hydrochloride	Cysteine Protease inhibitor hydrochloride is an inhibitor of cysteine protease. IC50 & Target: Cysteine Protease
M14305	Cysteine Protease inhibitor	Cysteine Protease inhibitor is an inhibitor of cysteine protease. IC50 & Target: Cysteine Protease
M14304	3-Epiursolic Acid	3-Epiursolic Acid is a triterpenoid isolated from Myrtaceae, acts as a competitive inhibitor of cathepsin L (ICIC50, 6.5 μM; Ki, 19.5 μM), with no obvious effect on cathepsin B.
M10280	L006235	L006235 (L235) is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S.
M9353	N-Ethylmaleimide	N-Ethylmaleimide (NEM) is a cysteine protease inhibitor.
M6236	CA-074 Me	CA-074 Me is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor.
M5288	UK-371804	UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).
M5167	Calpeptin	Calpeptin is a potent, cell-permeable inhibitor of the Ca²⁺-dependent protease, calpain.
M3826	Papain	Papain is a cysteine protease of the peptidase C1 family.
M3636	Leupeptin hemisulfate	Leupeptin hemisulfate hemisulfate is the reversible inhibitor of lysosomal serine and cysteine proteinases; Leupeptin; inhibition of cathepsin B(Ki=6 nM), calpain(Ki=10 nM), trypsin (Ki=35 nM), plasmin (Ki=3.4 μM) and kallikrein (Ki=19 μM) had no effect on chymotrypsin, elastase, renin, or pepsin.
M2600	Balicatib	Balicatib is a potent and selective inhibitor of cathepsin K; 10-100-fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S.
M2376	Aloxistatin	Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor.
M1985	Odanacatib	Odanacatib (MK-0822) is a potent and reversible covalent inhibitor of CathepsinK (CatK) with an IC50 of 0.2 nM/1 nM for human/rabbit cathepsin B, L, and S and is highly selective.

Signaling Pathways

Product Type

Cathepsin Cathepsin

Get to Know Us

Customer Support

Resources

Contact Us