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Cathepsin Cathepsin

Cat.No.  Name Information
M9353 N-Ethylmaleimide N-Ethylmaleimide (NEM) is a cysteine protease inhibitor.
M3636 Leupeptin hemisulfate Leupeptin hemisulfate hemisulfate is the reversible inhibitor of lysosomal serine and cysteine proteinases; Leupeptin; inhibition of cathepsin B(Ki=6 nM), calpain(Ki=10 nM), trypsin (Ki=35 nM), plasmin (Ki=3.4 μM) and kallikrein (Ki=19 μM) had no effect on chymotrypsin, elastase, renin, or pepsin.
M2497 Cathepsin Inhibitor 1 Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
M1985 Odanacatib Odanacatib (MK-0822) is a potent and reversible covalent inhibitor of CathepsinK (CatK) with an IC50 of 0.2 nM/1 nM for human/rabbit cathepsin B, L, and S and is highly selective.
M14308 SID 26681509 quarterhydrate SID 26681509 quarterhydrate is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC50 of 56 nM.
M14307 LY 3000328 LY 3000328 is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively.
M14306 Cysteine Protease inhibitor hydrochloride Cysteine Protease inhibitor hydrochloride is an inhibitor of cysteine protease. IC50 & Target: Cysteine Protease
M14305 Cysteine Protease inhibitor Cysteine Protease inhibitor is an inhibitor of cysteine protease. IC50 & Target: Cysteine Protease
M10280 L006235 L006235 (L235) is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S.
M9318 Chymostatin Chymostatin is a chymotryptase-like serine proteases inhibitor, with Ki values of 9.36 and 13.1 nM for chymotrypsin and chymase, respectively.
M6236 CA-074 Me CA-074 Me is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor.
M5288 UK-371804 UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).
M4767 aurantiamide-acetate Aurantiamide acetate is a selective and orally active cathepsin inhibitor isolated from Portulaca Oleracea L. Aurantiamide acetate has anti-inflammatory activity and can be used to study inflammatory diseases.
M3657 Pepstatin A (Pepstatin) Pepstatin A (Pepstatin) is a specific inhibitor of aspartic proteases produced by actinomycetes, which can inhibit hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease with IC50 values of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM, respectively.
M2823 Loxistatin Acid(E-64C) Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
M2600 Balicatib Balicatib is a potent and selective inhibitor of cathepsin K; 10-100-fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S.
M2376 Aloxistatin Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor.
M42307 Z-Phe-Arg-pNA Z-Phe-Arg-pNA is a substrate of Cathepsin L.
M42306 LN5P45 LN5P45 is an OTUB2 inhibitor (IC50: 2.3 μM).
M42305 TSC25 TSC25 is a potent cruzipain (CZP) inhibitor, with an IC50 of 3.34 nM and a pIC50 of 8.48.

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