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Cysteine Protease inhibitor hydrochloride

Cat. No. M14306
Cysteine Protease inhibitor hydrochloride Structure
Size Price Availability
5mg USD 420  USD420 1-2 Weeks
10mg USD 600  USD600 1-2 Weeks
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Quality Control & Documentation
Biological Activity

Cysteine Protease inhibitor hydrochloride is an inhibitor of cysteine protease. IC50 & Target: Cysteine Protease

Chemical Information
Molecular Weight 338.79
Solubility (25°C) DMSO 50 mg/mL
Storage 2-8°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Peng Yu, et al. [Effects of ropivacaine hydrochloride on the proliferation, invasion and apoptosis of osteosarcoma cells and its mechanism]

[2] Wei-Chung Chiou, et al. Repurposing existing drugs: identification of SARS-CoV-2 3C-like protease inhibitors

[3] Magdalena Gorska, et al. Geldanamycin and its derivatives as Hsp90 inhibitors

[4] I Berdowska, et al. Activity of cysteine protease inhibitors in human brain tumors

[5] J Brzin, et al. Clitocypin, a new type of cysteine proteinase inhibitor from fruit bodies of mushroom clitocybe nebularis

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Keywords: Cysteine Protease inhibitor hydrochloride supplier, Cathepsin, inhibitors, activators

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