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SID 26681509 quarterhydrate

Cat. No. M14308

All AbMole products are for research use only, cannot be used for human consumption.

SID 26681509 quarterhydrate Structure
Size Price Availability
1mg USD 195  USD195 1-2 Weeks
5mg USD 580  USD580 1-2 Weeks
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Quality Control & Documentation
Biological Activity

SID 26681509 quarterhydrate is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC50 of 56 nM. SID 26681509 quarterhydrate inhibits in vitro propagation of malaria parasite Plasmodium falciparum and inhibits Leishmania major with IC50s of 15.4 μM and 12.5 μM, respectively. SID 26681509 quarterhydrate shows no inhibitory activity against cathepsin G.

Chemical Information
Molecular Weight 544.16
Solubility (25°C) DMSO 50 mg/mL
Ethanol 5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Thea Bismo Strm, et al. Bone morphogenetic protein 1 cleaves the linker region between ligand-binding repeats 4 and 5 of the LDL receptor and makes the LDL receptor non-functional

[2] Grant R Campbell, et al. Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy

[3] Parag P Shah, et al. Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L

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  Catalog
Abmole Inhibitor Catalog




Keywords: SID 26681509 quarterhydrate supplier, Cathepsin, inhibitors, activators

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