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Cathepsin Cathepsin

Cat.No.  Name Information
M2497 Cathepsin Inhibitor 1 Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
M9353 N-Ethylmaleimide N-Ethylmaleimide (NEM) is a cysteine protease inhibitor.
M3636 Leupeptin hemisulfate Leupeptin hemisulfate hemisulfate is the reversible inhibitor of lysosomal serine and cysteine proteinases; Leupeptin; inhibition of cathepsin B(Ki=6 nM), calpain(Ki=10 nM), trypsin (Ki=35 nM), plasmin (Ki=3.4 μM) and kallikrein (Ki=19 μM) had no effect on chymotrypsin, elastase, renin, or pepsin.
M1985 Odanacatib Odanacatib (MK-0822) is a potent and reversible covalent inhibitor of CathepsinK (CatK) with an IC50 of 0.2 nM/1 nM for human/rabbit cathepsin B, L, and S and is highly selective.
M53923 N-CBZ-Phe-Arg-AMC N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes.
M52672 Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 is a cathepsin D substrate, that can be used for cathepsin D FRET assay.
M52671 (S, S)-Z-FA-FMK (S,S)-Z-FA-FMK is a cell-permeable, irreversible cathepsin B inhibitor.
M52670 H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen.
M52669 Z-Leu-Leu-Leu-fluoromethyl ketone Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) is a cysteine protease inhibitor.
M52668 Cathepsin D and E FRET Substrate Cathepsin D and E FRET Substrate is a fluorogenic substrate for cathepsins D and E and not for B, H or L.
M52667 Z-Leu-Tyr-Chloromethylketone Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor.
M52665 Z-Phe-Ala-diazomethylketone Z-Phe-Ala-diazomethylketone binds directly to Aβ42 monomers and small oligomers.
M52664 Z-Phe-Phe-Diazomethylketone Z-Phe-Phe-Diazomethylketone is a selective inhibitor of cathepsin L.
M52663 Ac-Leu-Val-Lys-Aldehyde Ac-Leu-Val-Lys-Aldehyde is a potent cathepsin B inhibitor with IC50s of 4 nM.
M52662 Cathepsin K inhibitor 5 Cathepsin K inhibitor 5 is a potent Cathepsin K inhibitor.
M52661 Suc-Val-Pro-Phe-pNA Suc-Val-Pro-Phe-pNA is a substrate for cathepsin G and can be used to detect the activity of this enzyme.
M52660 Hepcidin-1 (mouse) Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis.
M52659 Z-Leu-Leu-Arg-AMC Z-Leu-Leu-Arg-AMC is a peptide substrate of cathepsin S.
M52658 Cathepsin L-IN-3 Cathepsin L-IN-3 is a tripeptide-sized cathepsin L inhibitor.
M52657 Cathepsin L-IN-4 Cathepsin L-IN-4 is an inhibitor of cathepsin L with IC50 at nanomolar concentrations.
M52656 Z-FG-NHO-BzOME Z-FG-NHO-BzOME is a cysteine protease inhibitor that selectively inhibits cathepsin B, cathepsin L, cathepsin S, and papain.
M52655 Z-Arg-Arg-AMC Z-Arg-Arg-AMC is a selective substrate of cathepsin B.
M52654 Z-Arg-Arg-pNA Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity.
M52653 Arg-Arg-AMC Arg-Arg-AMC is a highly selective substrate of Cathepsin B.




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