Cat.No. | Name | Information |
---|---|---|
M2497 | Cathepsin Inhibitor 1 | Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. |
M9353 | N-Ethylmaleimide | N-Ethylmaleimide (NEM) is a cysteine protease inhibitor. |
M3636 | Leupeptin hemisulfate | Leupeptin hemisulfate hemisulfate is the reversible inhibitor of lysosomal serine and cysteine proteinases; Leupeptin; inhibition of cathepsin B(Ki=6 nM), calpain(Ki=10 nM), trypsin (Ki=35 nM), plasmin (Ki=3.4 μM) and kallikrein (Ki=19 μM) had no effect on chymotrypsin, elastase, renin, or pepsin. |
M1985 | Odanacatib | Odanacatib (MK-0822) is a potent and reversible covalent inhibitor of CathepsinK (CatK) with an IC50 of 0.2 nM/1 nM for human/rabbit cathepsin B, L, and S and is highly selective. |
M53923 | N-CBZ-Phe-Arg-AMC | N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes. |
M52672 | Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 | Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 is a cathepsin D substrate, that can be used for cathepsin D FRET assay. |
M52671 | (S, S)-Z-FA-FMK | (S,S)-Z-FA-FMK is a cell-permeable, irreversible cathepsin B inhibitor. |
M52670 | H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH | H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. |
M52669 | Z-Leu-Leu-Leu-fluoromethyl ketone | Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) is a cysteine protease inhibitor. |
M52668 | Cathepsin D and E FRET Substrate | Cathepsin D and E FRET Substrate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. |
M52667 | Z-Leu-Tyr-Chloromethylketone | Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor. |
M52665 | Z-Phe-Ala-diazomethylketone | Z-Phe-Ala-diazomethylketone binds directly to Aβ42 monomers and small oligomers. |
M52664 | Z-Phe-Phe-Diazomethylketone | Z-Phe-Phe-Diazomethylketone is a selective inhibitor of cathepsin L. |
M52663 | Ac-Leu-Val-Lys-Aldehyde | Ac-Leu-Val-Lys-Aldehyde is a potent cathepsin B inhibitor with IC50s of 4 nM. |
M52662 | Cathepsin K inhibitor 5 | Cathepsin K inhibitor 5 is a potent Cathepsin K inhibitor. |
M52661 | Suc-Val-Pro-Phe-pNA | Suc-Val-Pro-Phe-pNA is a substrate for cathepsin G and can be used to detect the activity of this enzyme. |
M52660 | Hepcidin-1 (mouse) | Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. |
M52659 | Z-Leu-Leu-Arg-AMC | Z-Leu-Leu-Arg-AMC is a peptide substrate of cathepsin S. |
M52658 | Cathepsin L-IN-3 | Cathepsin L-IN-3 is a tripeptide-sized cathepsin L inhibitor. |
M52657 | Cathepsin L-IN-4 | Cathepsin L-IN-4 is an inhibitor of cathepsin L with IC50 at nanomolar concentrations. |
M52656 | Z-FG-NHO-BzOME | Z-FG-NHO-BzOME is a cysteine protease inhibitor that selectively inhibits cathepsin B, cathepsin L, cathepsin S, and papain. |
M52655 | Z-Arg-Arg-AMC | Z-Arg-Arg-AMC is a selective substrate of cathepsin B. |
M52654 | Z-Arg-Arg-pNA | Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity. |
M52653 | Arg-Arg-AMC | Arg-Arg-AMC is a highly selective substrate of Cathepsin B. |
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