Free shipping on all orders over $ 500

Cysteine Protease inhibitor

Cat. No. M14305
Cysteine Protease inhibitor Structure
Size Price Availability
5mg USD 330  USD330 1-2 Weeks
10mg USD 480  USD480 1-2 Weeks
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Cysteine Protease inhibitor is an inhibitor of cysteine protease. IC50 & Target: Cysteine Protease

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 302.33
Formula
CAS Number 921625-62-9
Purity >99%
Solubility DMSO 50 mg/mL
Storage at -20°C
References

[1] Dbora do Carmo Linhares, et al. Novel Cysteine Protease Inhibitor Derived from the Haementeria vizottoi Leech: Recombinant Expression, Purification, and Characterization

[2] Thị Lam Thi, et al. Fowlerstefin, a cysteine protease inhibitor of Naegleria fowleri, induces inflammatory responses in BV-2 microglial cells in vitro

[3] Nana Wei, et al. A Tick Cysteine Protease Inhibitor RHcyst-1 Exhibits Antitumor Potential

[4] Lin Chen, et al. Cysteine protease inhibitor of Schistosoma japonicum - A parasite-derived negative immunoregulatory factor

[5] Mika K Lindvall. Molecular modeling in cysteine protease inhibitor design

Related Cathepsin Products
LHVS

LHVS is a potent, non-selective, irreversible, cell-permeable inhibitor of cysteine protease and cathepsin. lHVS reduces actin ring formation. lHVS inhibits T. gondii invasion with an IC50 of 10 μM.

Z-LVG-CHN2

Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase.

SID 26681509 quarterhydrate

SID 26681509 quarterhydrate is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC50 of 56 nM.

LY 3000328

LY 3000328 is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively.

Cysteine Protease inhibitor hydrochloride

Cysteine Protease inhibitor hydrochloride is an inhibitor of cysteine protease. IC50 & Target: Cysteine Protease

  Catalog
Abmole Inhibitor Catalog




Keywords: Cysteine Protease inhibitor supplier, Cathepsin, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.