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 About 29 results found for searched term "CY7" (0.06 seconds)

Cat.No.  Name Target
M1700 Momelotinib (CYT387) JAK
LM-1149; Momelotinib; CYT 11387
Momelotinib (CYT387) is a small-molecule, ATP-competitive JAK1/JAK2 inhibitor with IC50 of 11 and 18 nM respectively.
M2052 Decitabine DNA Methyltransferase
5-Aza-2'-deoxycytidine; NSC 127716; 5-AZA-CdR
Decitabine (5-Aza-2'-deoxycytidine) is a potent inhibitor of DNA methylation for the treatment of myelodysplastic syndromes.
M2547 Cyromazine Metabolite/Endogenous Metabolite
Cyromazin; CGA-72662
Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide.
M2849 Microcystin-LR Phosphatase
Cyanoginosin-LR; MC-LR; Toxin T 17 (Microcystis aeruginosa)
Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
M2929 PF-4981517 Cytochrome P450 (e.g. CYP17)
CYP3cide, PF-04981517
PF-4981517 is a potent and selective inhibitor of CYP3A4 (P450) with IC50 of 0.03 μM, exhibits >500-fold selectivity over CYP3A5 and CYP3A7.
M3492 CYT997 Microtubule
CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines.
M3827 CY7 Fluorescent Dye
Sulfo-Cyanine7 carboxylic acid
Cy7 (Sulfo-Cyanine7) is a fluorescence labeling agent (Ex=750 nm, Em=773 nm), used to label proteins, antibodies, peptides, and oligonucleotides.
M4935 3-Cyano-7-ethoxycoumarin Cytochrome P450 (e.g. CYP17)
3-Cyano-7-ethoxycoumarin is a fluorogenic cytochrome P-450 substrate that generates blue fluorescent product upon enzyme cleavage.
M6638 Cyanine 7, SE Others
Cyanine 7, SE is a near-infrared fluorescent dye for labeling of amines; supplied as NHS ester.
M8432 CYM50769 Neuropeptide Receptor
CYM50769 is a potent, specific antagonist of the Neuropeptide B and Neuropeptide W receptor, NPBWR1 (IC50 = 120 nM).
M9153 ACY-738 HDAC
ACY-738 is a potent, selective and orally-bioavailable HDAC6 inhibitor, with an IC50s of 1.7 nM.
M10079 ACY-775 HDAC
ACY-775 is a potent and selective HDAC6 inhbiitor with IC50 of 7.5 nM.
M10233 ((Cys31,Nva34)-Neuropeptide Y (27-36))2 Neuropeptide Receptor
BWX 46
((Cys31,Nva34)-Neuropeptide Y (27-36))2, also called BWX 46, is a neuropeptide Y (NPY) Y5 receptor selective agonist.
M10833 Ibrexafungerp Anti-infection
SCY-078; MK-3118
Ibrexafungerp is a novel, orally available glucan synthase inhibitor with in vitro activity against many echinocandin-resistant Candida strains.
M13671 ACY-957 HDAC
ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9.
M13852 Momelotinib sulfate JAK
CYT387 sulfate salt
Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM). In addition, Momelotinib is an inhibitor of activin A receptor type I (ACVR1). It may be used in studies related to myelofibrosis.
M15040 Recombinant Human MCP-3/CCL7 (CHO) Recombinant Proteins
C-C motif chemokine 7; Small inducible cytokine A7
Chemokine (C-C Motif) Ligand 7 (CCL7) is a small cytokine formerly known as monocyte specific chemokine 3 (McP-3). Protein structure: MCP 3 (GLN34-LEU109),Accession # : Q7Z7Q8.
M16351 2α-Acetoxy-14,15-cyclopimara-7β,16-diol Diterpenoids
M16893 erythro-Guaiacylglycerol β-sinapyl ether 7-O-glucoside Lignans
erythro-Guaiacylglycerol β-sinapyl ether 7-O-glucoside
M25434 Tranylcypromine (2-PCPA) HCl (≥97.0%) Monoamine Oxidase
SKF-385 HCl; Trans 2-Phenylcyclopropylamine Hydrochloride
Tranylcypromine HCl is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively. Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC50s of 20.7, 2.3 and 0.95 μM, respectively.
M28232 CYM50179  LPL Receptor
CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC50 of 46 nM.
M30766 CYM-5478  LPL Receptor
CYM-5478 is a potent and highly selective S1P2 agonist with an EC50 of 119 nM in a TGFα-shedding assay. CYM-5478 protects neural-derived cell lines against Cisplatin toxicity.
M30903 Lexibulin dihydrochloride Microtubule
CYT-997 dihydrochloride
Lexibulin dihydrochloride (CYT-997 dihydrochloride) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo. Lexibulin dihydrochloride induces cell apoptosis and induces mitochondrial ROS generation in GC cells.
M31332 Cyanine7.5 maleimide Fluorescent Dye
Cyanine7.5 maleimide (CY7.5-maleimide) is a commonly used phalloidin dye, and its labeled product has an Ex/Em of 788/808 nm, respectively.
M43153 CYCA-117-70 Others
CYCA-117-70 is a DCAF1 ligand (KD: 70 μM).
M53490 Cys-TAT(47-57) Anti-infection
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.
M53493 (Cys47)-HIV-1 tat Protein (47-57) Anti-infection
(Cys47)-HIV-1 tat Protein (47-57) has membrane translocation function and can be used to derivatize the surface of magnetic pharmaceuticals and substantially facilitated their uptake into target cells.
M53913 Smcy HY Peptide (738-746) Others
Smcy HY Peptide (738-746) is a H2-Db-restricted peptide corresponding to amino acids 738-746 of Smcy protein.
M54460 Acyl Carrier Protein (ACP) (65-74) Others
Acyl Carrier Protein (ACP) (65-74) is an active acyl carrier protein (ACP) fragment.

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