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Cyromazine

Cat. No. M2547
Cyromazine Structure
Synonym:

Cyromazin; CGA-72662

Size Price Availability Quantity
200mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide.

Chemical Information
Molecular Weight 166.18
Formula C6H10N6
CAS Number 66215-27-8
Solubility (25°C) DMSO 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Xiaofeng Ji, et al. Evaluation of cyromazine transferred from feed to chicken products and subsequent assessment of dietary risks to Chinese consumers

[2] Honghong Guo, et al. Elucidating the microbiological characteristics of cyromazine affecting the nitrogen cycle during aerobic composting of pig manure

[3] Duhan Fu, et al. Dissipation behavior, residue distribution and dietary risk assessment of cyromazine, acetamiprid and their mixture in cowpea and cowpea field soil

[4] Takashi Hatakeyama, et al. Biodegradation of cyromazine by melamine-degrading bacteria

[5] Hafiz Azhar Ali Khan, et al. Cyromazine resistance in a field strain of house flies, Musca domestica L.: Resistance risk assessment and bio-chemical mechanism

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Keywords: Cyromazine, Cyromazin; CGA-72662 supplier, inhibitors, activators

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