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CY7

Cat. No. M3827
CY7 Structure
Synonym:

Sulfo-Cyanine7 carboxylic acid

Size Price Availability Quantity
5mg USD 172  USD172 In stock
10mg USD 270  USD270 In stock
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Quality Control & Documentation
  • Purity: Biological Stain
  • COA
  • MSDS
Biological Activity

Cy7 (Sulfo-Cyanine7) is a fluorescence labeling agent (Ex=750 nm, Em=773 nm), used to label proteins, antibodies, peptides, and oligonucleotides.

Chemical Information
Molecular Weight 682.85
Formula C35H42N2O8S2
CAS Number 943298-08-6
Solubility (25°C) DMSO ≥ 30 mg/mL
Storage 2-8°C, dry, protect from light, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Lim B, et al. Theranostics. A Unique Recombinant Fluoroprobe Targeting Activated Platelets Allows In Vivo Detection of Arterial Thrombosis and Pulmonary Embolism Using a Novel Three-Dimensional Fluorescence Emission Computed Tomography (FLECT) Technology.

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