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Lexibulin dihydrochloride (CYT-997 dihydrochloride) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo. Lexibulin dihydrochloride induces cell apoptosis and induces mitochondrial ROS generation in GC cells.
| Molecular Weight | 507.46 |
| Formula | C24H32Cl2N6O2 |
| CAS Number | 917111-49-0 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. |
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