About 30 results found for searched term "CY3" (0.023 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1700 | Momelotinib (CYT387) | JAK |
| LM-1149; Momelotinib; CYT 11387 | ||
| Momelotinib (CYT387) is a small-molecule, ATP-competitive JAK1/JAK2 inhibitor with IC50 of 11 and 18 nM respectively. | ||
| M25536 | Recombinant Human CXCL13/BCA-1 (E. coli) | Cytokines and Growth Factors |
| CXC chemokine BLC; Small-inducible cytokine B13 | ||
| CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Determined by a chemotaxis bioassay using human B cells, the biological activity is in a concentration range of 1.0-10 ng/ml. | ||
| M2929 | PF-4981517 | Cytochrome P450 (e.g. CYP17) |
| CYP3cide, PF-04981517 | ||
| PF-4981517 is a potent and selective inhibitor of CYP3A4 (P450) with IC50 of 0.03 μM, exhibits >500-fold selectivity over CYP3A5 and CYP3A7. | ||
| M3347 | Zalcitabine | Reverse Transcriptase |
| ddC; Dideoxycytidine; 2',3'-Dideoxycytidine | ||
| Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI). | ||
| M3598 | Penicillamine | Cuproptosis |
| DL-beta-Mercaptovaline; 3,3-Dimethyl-DL-cysteine; 3-Sulfanylvaline | ||
| Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine reduces free copper and reduces oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. | ||
| M3646 | Cyclobenzaprine hydrochloride | 5-HT Receptor |
| Cyclobenzaprine HCl; MK130 hydrochloride | ||
| Cyclobenzaprine hydrochloride is a skeletal muscle relaxant and a central nervous system (CNS) depressant. | ||
| M4554 | Kuromanin chloride | Others |
| Chrysontemin; Cyanidin 3-O-glucoside chloride | ||
| Kuromanin 3-O-glucoside (Kuromanin chloride), derived from mulberry leaves, has the effect of increasing blood glucose concentration and maintaining lipid metabolism balance to reduce obesity. | ||
| M4907 | Doxycycline Hyclate | MMP |
| Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031 | ||
| Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. | ||
| M5479 | Carsalam | Others |
| Carbonylsalicylamide; 2H-1,3-Benzoxazine-2,4(3H)-dione | ||
| Carsalam (Carbonylsalicylamide) is a non-steroidal anti-inflammatory compound. | ||
| M5651 | Flucytosine | DNA/RNA Synthesis |
| 5-Fluorocytosine; NSC 103805; Ro 2-9915 | ||
| Flucytosine (5-Fluorocytosine, 5-FC, Ancobon), a fluorinated pyrimidine analogue, is an antifungal drug. | ||
| M6359 | 8-Cyclopentyl-1,3-dimethylxanthine | Adenosine Receptor |
| 8-Cyclopentyl-1,3-dimethylxanthine is a high affinity adenosine A 1 receptor antagonist. | ||
| M6567 | CCCP | Apoptosis |
| Carbonyl cyanide 3-chlorophenylhydrazone; Carbonyl Cyanide m-Chlorophenylhydrazone | ||
| CCCP is a oxidative phosphorylation uncoupler. CCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation. | ||
| M8431 | CYM50358 | S1P Receptor |
| CYM50358 is a potent, selective antagonist of the sphingosine-1-phosphate receptor 4 (S1P4). | ||
| M9153 | ACY-738 | HDAC |
| ACY-738 is a potent, selective and orally-bioavailable HDAC6 inhibitor, with an IC50s of 1.7 nM. | ||
| M10161 | PACAP (1-38) | Peptides |
| Pituitary Adenylate Cyclase Activating Polypeptide 38 | ||
| PACAP (1-38) is a highly potent PACAP receptor agonist (Kd = 100 pM), it stimulates adenylate cyclase and phagocytosis. | ||
| M10195 | MOG (35-55) (Mouse, rat) | Animal Modeling |
| Myelin Oligodendrocyte Glycoprotein (35-55) (Mouse, rat) | ||
| MOG (35-55) (Mouse, rat) is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat induces Th1 cytokine response as well as relatively high levels of IgG antibodies. | ||
| M10233 | ((Cys31,Nva34)-Neuropeptide Y (27-36))2 | Neuropeptide Receptor |
| BWX 46 | ||
| ((Cys31,Nva34)-Neuropeptide Y (27-36))2, also called BWX 46, is a neuropeptide Y (NPY) Y5 receptor selective agonist. | ||
| M10833 | Ibrexafungerp | Anti-infection |
| SCY-078; MK-3118 | ||
| Ibrexafungerp is a novel, orally available glucan synthase inhibitor with in vitro activity against many echinocandin-resistant Candida strains. | ||
| M11363 | Recombinant Human CYP3A4 (E.coli, N-His) | Cytokines and Growth Factors |
| Recombinant human CYP3A4 is an important member of cytochrome P45 enzyme superfamily, with 33 alleles. Systemic inflammation is associated with inhibition of CYP3A4 activity. | ||
| M13412 | Ethynylcytidine | DNA/RNA Synthesis |
| ECyD; TAS-106; 3'-C-Ethynylcytidine | ||
| Ethynylcytidine is a new nucleoside antimetabolite. A potent inhibitor of RNA synthesis, Ethynylcytidine has demonstrated strong antitumor activity in a variety of cancer models. | ||
| M13852 | Momelotinib sulfate | JAK |
| CYT387 sulfate salt | ||
| Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM). In addition, Momelotinib is an inhibitor of activin A receptor type I (ACVR1). It may be used in studies related to myelofibrosis. | ||
| M14119 | cGAMP diammonium | STING |
| Cyclic GMP-AMP diammonium; 3',3'-cGAMP diammonium | ||
| cGAMP (Cyclic GMP-AMPP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. | ||
| M14120 | cGAMP disodium | STING |
| Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium | ||
| cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. | ||
| M14561 | Recombinant Human MIP-5/CCL15 Protein (E. coli, aa 22-113, C-His) | Cytokines and Growth Factors |
| SCYA15; HCC-2; NCC-3 | ||
| Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. | ||
| M14642 | 2'-Deoxycytidine hydrochloride | Metabolite/Endogenous Metabolite |
| 2'-Deoxycytidine monohydrochloride; Deoxycytidine hydrochloride; NSC 83251 | ||
| 2'-Deoxycytidine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. | ||
| M14818 | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA | Peptides |
| MOG (35-55) (TFA) | ||
| Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (TFA) is a minor component of CNS myelin. | ||
| M31280 | CY3 | Fluorescent Dye |
| Sulfo-Cyanine3 | ||
| CY3 (Sulfo-Cyanine3) is a widely used, orange fluorescent marker for proteins and nucleic acids (λex=554, λem=568). | ||
| M17655 | 24-Hydroxy-25-ethoxy-3,4-secocycloart -4(28)-en-3-oic acid methyl ester | Triterpenoids |
| 24-Hydroxy-25-ethoxy-3,4-secocycloart -4(28)-en-3-oic acid methyl ester | ||
| M17687 | Cycloart-25-ene-3β,24-diol | Triterpenoids |
| Cycloart-25-ene-3β,24-diol | ||
| M17688 | Cycloart-23-ene-3β,25-diol | Triterpenoids |
| Cycloart-23-ene-3β,25-diol | ||
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