| Cat.No. | Name | Information |
|---|---|---|
| M1962 | Lenalidomide | Lenalidomide is a thalidomide analog known to display TNF-α secretion inhibition and possesses immunomodulatory properties. |
| M6224 | Etanercept | Etanercept is a dimer fusion protein that binds tumor necrosis factor (TNF) as a TNF inhibitor. Etanercept competitively inhibits the binding of TNF-α and TNF-β to TNF receptors on the cell surface, rendering tumor necrosis factor biologically inactive. |
| M4378 | Forsythoside B | Forsythoside B inhibits TNF-alpha, IL-6, IκB and modulate NF-κB. |
| M4240 | Shikonin | Shikonin (C.I. 75535, Anchusin, Anchusa acid, Alkanna Red, Isoarnebin 4, NSC 252844) is an effective and specific inhibitor of Pyruvate kinase M2 (PKM2). Shikonin is the main ingredient of Lithosia, a Chinese herb with a variety of biological activities. Shikonin acts as an anti-inflammatory by inhibiting tumor necrosis factor-α (TNF-α), Proteasome can inhibit the activation of nuclear factor-κB (NF-κB) signaling pathway. |
| M4022 | Hypaconitine | Hypaconitine is a highly toxic natural active ingredient isolated from aconitum species, which is widely used to study rheumatism. |
| M4021 | Mesaconitine | Mesaconitine is the main active ingredient of Aconitum and has many pharmaceutical effects. |
| M1545 | Infliximab | Infliximab is a purified, recombinant DNA-derived chimeric human-mouse IgG monoclonal antibody that blocks TNF-α interaction with TNF-α receptor 1 (TNFR1) and TNFR2. For the treatment of autoimmune diseases. Infliximab is available in BALB/ C or C57/Bl6 mice. |
| M54557 | Chilob7/4 | Chilob7/4 is a chimeric agonist anti-CD40 IgG1 antibody that can be used for tumor-related studies. |
| M54556 | VIB4920 | VIB4920 is a fusion protein that binds to CD40L on activated T cells and blocks the interaction of CD40L with CD40-expressing B cells and other possible binding substrates. |
| M54555 | ABBV-428 | ABBV-428 is a bispecific antibody targeting CD40/Mesothelin and can be used in studies related to solid tumors. |
| M53998 | TNF-α (31-45), human | TNF-α (31-45), human is a potent NF-kB pathway activator. |
| M53367 | LEESGGGLVQPGGSMK | LEESGGGLVQPGGSMK, a proteolysis peptide, is a component of Infliximab. |
| M53366 | Delmitide | Delmitide (RDP58) is an orally active d-isomer decapeptide with potent anti-inflammatory activity. |
| M53365 | Epobis | Epobis, a dendrimeric peptide, is a recombinant form of erythropoietin. |
| M49437 | PF-06480605 | PF-06480605 is an IgG1 human monoclonal antibody against TNF-like ligand 1A (TL1A, TNFSF15), which can be used in studies related to ulcerative colitis (UC). |
| M49436 | V565 | V565 is a novel antibody that specifically targets TNFα and can be used in studies related to Crohn's disease (CD). |
| M45266 | Linvoseltamab | Linvoseltamab is a bispecific antibody targeting BCMA (TNFRSF17) and CD3. Linvoseltamab is used in studies related to relapsed/refractory multiple myeloma (R/R MM). |
| M45222 | TEV’574 | TEV'574 is a TL1A antibody with a unique binding epitope that blocks TL1A binding to the DR3 receptor without affecting TL1A binding to the DcR3 pseudoreceptor. It can be used in studies related to ulcerative colitis and Crohn's disease. |
| M44749 | 5-Hydroxy-3',4',7-trimethoxyflavone | 7,3',4'-Tri-O-methylluteolin possesses potent anti-inflammatory effects in LPS-induced macrophage cell line mediated by inhibition of release of inflammatory mediators, NO, PGE2, and pro-inflammatory cytokines. |
| M43929 | Zigakibart | Zigakibart is an anti-APRIL monoclonal antibody that can be used in studies related to IgA nephropathy (IgAN). |
| M41608 | Fisetin quarterhydrate | Fisetin quarterhydrate is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects. |
| M41379 | BMS-561392 | BMS-561392 is a TNF alpha-converting enzyme (TACE) inhibitor. |
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