Inhibitors
Cat.No. | Name | Information |
---|---|---|
M11345 | Inclisiran | Inclisiran (ALN-PCSSC) is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. Inclisiran can be used in hyperlipidemia and cardiovascular disease (CVD) studies. |
M11343 | Pinostrobin | Pinostrobin is a flavonoid found in many plants and has antioxidant, anti-inflammatory, anticancer and neuroprotective properties. Pinostrobin is an effective INHIBITOR of PCSK9, which can inhibit the catalytic activity of PCSK9. Pinostrobin is a promising agent for cholesterol regulation and lipid management. |
M11214 | WNK463 | WNK463 is an oral WNK kinase inhibitor for WNK1, WNK2, WNK3, and WNK4 IC50 The values are 5 nM, 1 nM, 6 nM, and 9 nM, respectively. |
M10641 | FOY-251 mesylate | FOY-251 mesylate is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies. |
M10598 | SPHINX31 | SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1) with IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). |
M10198 | Zabedosertib | Zabedosertib is a serine/ threonine kinase inhibitor. |
M9648 | Empesertib | Empesertib (BAY1161909) is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase (IC50 of < 1 nM), with potential antineoplastic activity. |
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