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Serine/Threonine Protease Serine/Threonine Protease

Cat.No.  Name Information
M5219 AEBSF HCl AEBSF HCl is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.
M3651 Aprotinin Aprotinin is a small protein serine protease inhibitor which is used to reduce perioperative blood loss and transfusion.
M2952 PMSF PMSF is an irreversible serine/cysteine protease inhibitor.
M40518 Ulinastatin Ulinastatin Ulinastatin is an inhibitor of serine protease and urinary trypsin with anti-inflammatory activity and is used in studies related to pancreatitis, sepsis and septic shock.
M21530 Sebetralstat Sebetralstat is an orally active pro-adrenergic (PKa) inhibitor that may be used in studies related to hereditary angioedema (HAE).
M20773 BioE-1115 BioE-1115 is a highly selective and potent dual inhibitor of PAS kinase (PASK) and casein kinase 2α (CK2α) with IC50 of ~4 nM and ~10 μM, respectively.
M14534 WNK-IN-11 WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.
M14532 Avoralstat Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research.
M11505 7-Amino-4-methylcoumarin 7-amino-4-methylcoumarin (Coumarin 120) is used as a fluorescent probe for many serine proteases. Used for high performance liquid chromatographic labeling.
M11406 Berotralstat Berotralstat (BCX7353) was a second generation plasma kallikrein inhibitor with low toxicity and high specificity, and was used for the diagnosis of hereditary angioedema (HAE). Berotralstat works by blocking the enzyme activity of plasma Kallikrein that releases bradykinin, a major biological peptide that promotes swelling and pain associated with HAE attacks.
M11214 WNK463 WNK463 is an oral WNK kinase inhibitor for WNK1, WNK2, WNK3, and WNK4 IC50 The values are 5 nM, 1 nM, 6 nM, and 9 nM, respectively.
M10641 FOY-251 mesylate FOY-251 mesylate is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies.
M10198 Zabedosertib Zabedosertib is a serine/ threonine kinase inhibitor.
M9648 Empesertib Empesertib (BAY1161909) is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase (IC50 of < 1 nM), with potential antineoplastic activity.
M9595 Upamostat Upamostat (WX-671, umorestat) is a Urokinase-type Plasminogen Activator (uPA) inhibitor.
M9255 UKI-1 UKI-1 is a novel synthetic inhibitor of the urokinase-type plasminogen activator, which inhibits the invasive capacity of carcinoma cells with a Ki of 0.41 μM.
M5803 Nafamostat Mesylate Nafamostat Mesylate is a synthetic serine protease inhibitor with concomitant anticoagulant activity.
M54291 Phe-Pro-Ala-pNA Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase.
M52526 Dansyl-Glu-Gly-Arg-Chloromethylketone Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor, and inhibits serine/threonine proteases.
M52525 Fluorescent Substrate for Subtillsin Fluorescent Substrate for Subtillsin can be used to detect the enzyme activity of subtillsin.




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