|AEBSF HCl is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.
|Aprotinin is a small protein serine protease inhibitor which is used to reduce perioperative blood loss and transfusion.
|PMSF is an irreversible serine/cysteine protease inhibitor.
|Ulinastatin Ulinastatin is an inhibitor of serine protease and urinary trypsin with anti-inflammatory activity and is used in studies related to pancreatitis, sepsis and septic shock.
|Sebetralstat is an orally active pro-adrenergic (PKa) inhibitor that may be used in studies related to hereditary angioedema (HAE).
|BioE-1115 is a highly selective and potent dual inhibitor of PAS kinase (PASK) and casein kinase 2α (CK2α) with IC50 of ~4 nM and ~10 μM, respectively.
|WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.
|Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research.
|7-amino-4-methylcoumarin (Coumarin 120) is used as a fluorescent probe for many serine proteases. Used for high performance liquid chromatographic labeling.
|Berotralstat (BCX7353) was a second generation plasma kallikrein inhibitor with low toxicity and high specificity, and was used for the diagnosis of hereditary angioedema (HAE). Berotralstat works by blocking the enzyme activity of plasma Kallikrein that releases bradykinin, a major biological peptide that promotes swelling and pain associated with HAE attacks.
|WNK463 is an oral WNK kinase inhibitor for WNK1, WNK2, WNK3, and WNK4 IC50 The values are 5 nM, 1 nM, 6 nM, and 9 nM, respectively.
|FOY-251 mesylate is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies.
|Zabedosertib is a serine/ threonine kinase inhibitor.
|Empesertib (BAY1161909) is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase (IC50 of < 1 nM), with potential antineoplastic activity.
|Upamostat (WX-671, umorestat) is a Urokinase-type Plasminogen Activator (uPA) inhibitor.
|UKI-1 is a novel synthetic inhibitor of the urokinase-type plasminogen activator, which inhibits the invasive capacity of carcinoma cells with a Ki of 0.41 μM.
|Nafamostat Mesylate is a synthetic serine protease inhibitor with concomitant anticoagulant activity.
|Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase.
|Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor, and inhibits serine/threonine proteases.
|Fluorescent Substrate for Subtillsin
|Fluorescent Substrate for Subtillsin can be used to detect the enzyme activity of subtillsin.
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