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UKI-1

Cat. No. M9255

All AbMole products are for research use only, cannot be used for human consumption.

UKI-1 Structure
Size Price Availability Quantity
5mg USD 400  USD400 In stock
10mg USD 600  USD600 In stock
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Quality Control & Documentation
Biological Activity

UKI-1 is a novel synthetic inhibitor of the urokinase-type plasminogen activator, which inhibits the invasive capacity of carcinoma cells with a Ki of 0.41 μM.

Chemical Information
Molecular Weight 613.81
Formula C32H47N5O5S
CAS Number 220355-63-5
Form Solid
Solubility (25°C) DMSO: ≥ 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ertongur S, et al. Int J Cancer. Inhibition of the invasion capacity of carcinoma cells by WX-UK1, a novel synthetic inhibitor of the urokinase-type plasminogen activator system.

[2] Zeslawska E, et al. J Mol Biol. Crystals of the urokinase type plasminogen activator variant beta(c)-uPAin complex with small molecule inhibitors open the way towards structure-based dr ug design.

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Keywords: UKI-1 supplier, Serine/Threonine Protease, inhibitors, activators

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