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Ulinastatin

Cat. No. M40518
Ulinastatin Structure
Synonym:

Uristatin; UTI

Size Price Availability Quantity
5mg USD 120  USD120 In stock
10mg USD 180  USD180 In stock
25mg USD 400  USD400 In stock
50mg USD 720  USD720 In stock
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Quality Control & Documentation
Biological Activity

Ulinastatin Ulinastatin is an inhibitor of serine protease and urinary trypsin with anti-inflammatory activity and is used in studies related to pancreatitis, sepsis and septic shock.

Chemical Information
Formula C13H16O3
CAS Number 80449-31-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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  Catalog
Abmole Inhibitor Catalog




Keywords: Ulinastatin, Uristatin; UTI supplier, Serine/Threonine Protease, inhibitors, activators


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