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Reverse Transcriptase Reverse Transcriptase

Inhibitors

Cat.No.  Name Information
M21356 Ulonivirine Ulonivirine (MK-8507) is an orally active non-nucleoside reverse transcriptase inhibitor with high antiviral activity.Ulonivirine is used in the study of HIV-1 infection.
M20784 Tenofovir alafenamide fumarate Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.
M20783 Tenofovir alafenamide hemifumarate Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.
M20702 Alovudine 3'-Fluoro-3'-deoxythymidine (Alovudine) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.
M20577 Doravirine (MK-1439) Doravirine is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay. It is highly specific with minimum off-target activities.
M20483 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is a HIV-1 RT (HIV reverse transcriptase) inhibitor.
M20468 Entecavir Entecavir, a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).
M5605 Efavirenz Efavirenz is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity.
M5050 Adefovir Dipivoxil Adefovir Dipivoxil is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV).
M3381 Nevirapine Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.
M3355 Didanosine Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.
M3352 Lamivudine Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor with an IC50 of 2.7 mM.
M3347 Zalcitabine Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).
M3342 Emtricitabine Emtricitabine is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM.
M3205 Zidovudine Zidovudine is a reverse transcriptase inhibitor.
M2980 Rilpivirine Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and used to treat HIV-1 infection.
M2694 Etravirine Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
M2575 Dapivirine Dapivirine is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM.
M2363 Abacavir sulfate Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.
M2137 Stavudine Stavudine (D4T) is a potent inhibitor of HIV-1 reverse transcriptase in vitro.



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