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PDE Phosphodiesterase

Cat.No.  Name Information
M2030 Apremilast Apremilast is a novel, orally available small molecule inhibitor of PDE4 with IC50 of 74 nM.
M6804 IBMX IBMX is a pDE inhibitor (non-selective) with IC50 values of 6.5±1.2, 26.3±3.9 and 31.7±5.3 μM for PDE3, 4 and 5 respectively.
M1906 Piclamilast Piclamilast (RP 73401) is a potent and selective inhibitor of phosphodiesterase (PDE) 4.
M1871 Roflumilast Roflumilast (trade names Daxas, Daliresp) is a novel and selective, long-acting inhibitor of phosphodiesterase 4 (PDE-4).
M1734 BAY-60-7550 BAY-60-7550 is a potent PDE2 inhibitor with IC50 values of 2.0 nM (bovine) and 4.7 nM (human).
M1728 GSK256066 GSK256066 is a selective phosphodiesterase 4 (PDE4)inhibitor with an IC50 of 3.2 pM. *The compound is unstable in solutions, freshly prepared is recommended
M49421 ME-3183 ME-3183 is an oral selective PDE4 inhibitor with anti-inflammatory activity for studies related to plaque psoriasis.
M49420 ART-648 ART-648 is a PDE4 inhibitor that may be used in studies related to non-alcoholic steatohepatitis.
M49402 (E/Z)-HA155 (E/Z)-HA155 is a potent Autotaxin (ATX) type I inhibitor for studies related to cancer, fibrous disorders, inflammation, pain and angiogenesis.
M49401 Autotaxin-IN-3 Autotaxin-IN-3 is an Autotaxin(ATX) inhibitor with an IC50 value of 2.4 nM.
M49400 HA155 HA155 is a potent and selective ATX inhibitor with an IC50 value of 5.7 nM.
M49398 ATX inhibitor 5 ATX inhibitor 5 is a potent, orally active inhibitor of Autotaxin (ATX) with an IC50 of 15.3 nM.Additionally, AATX inhibitor 5 exhibits anti-hepatic fibrosis activity and significantly reduces CCl4-induced hepatic fibrosis.
M49394 BBT-877 BBT-877 is an oral small molecule autotaxin (ATX) inhibitor for use in studies related to non-alcoholic steatohepatitis (NASH) and idiopathic pulmonary fibrosis (IPF).
M44885 Ilexsaponin B2 Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook.
M42569 Enpp-1-IN-16 Enpp-1-IN-16 is an ENPP1 inhibitor.
M42568 cis-Tadalafil cis-Tadalafil is a PDE5 inhibitor (IC50: 0.09 μM).
M42567 Motapizone Motapizone (NAT 05-239) is a selective PDE3 inhibitor.
M42566 PDE4-IN-13 PDE4-IN-13 is a PDE4 inhibitor with an IC50 of 1.56 μM.
M42565 PDE1-IN-5 PDE1-IN-5 is a selective PDE1C inhibitor (IC50: 15 nM).
M42564 CD00509 CD00509 is a Tdp1 inhibitor, with an IC50 value of 0.71 μM.
M42563 PDE5-IN-10 PDE5-IN-10 is a potent PDE5 inhibitor with an IC50 of 20 nM.
M42562 ATX inhibitor 18 ATX inhibitor 18 is a potent ATX inhibitor with an IC50 value of 24.2 nM.




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