All AbMole products are for research use only, cannot be used for human consumption.
Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity.
| Molecular Weight | 278.31 |
| Formula | C13H18N4O3 |
| CAS Number | 6493-05-6 |
| Form | Solid |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] A J Lyons, et al. Pentoxifylline - a review of its use in osteoradionecrosis
[3] Seray Klc akmak, et al. Pentoxifylline use in dermatology
[4] Kate Whitfield, et al. Pentoxifylline for alcoholic hepatitis
| Related PDE Products |
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MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM. |
| MMPX
MMPX is a potent PDE1 inhibitor. |
| T-0156
T-0156 is a potent and selective phosphodiesterase type 5 (PDE5) inhibitor. |
| TPN171
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| Mesopram
Mesopram (Daxalipram) is an orally active phosphodiesterase (PDE) 4 inhibitor. |
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