About 8 results found for searched term "PDE" (0.057 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21158 | Vepdegestrant (ARV-471) | PROTAC |
| ARV471; 2229711-08-2; PF-07850327 | ||
| Vepdegestrant (ARV-471) is an oral estrogen receptor PROTAC protein degrader for breast cancer.ARV-471 is a heterobifunctional molecule that promotes the interaction between estrogen receptor alpha and intracellular E3 ligase complexes.ARV-471 causes ubiquitination and subsequent degradation of the estrogen receptor via the proteasome.ARV-471 potently degrades ER-positive The ER in breast cancer cell lines is potently degraded by ARV-471 with a DC50 value of approximately 2 nM. | ||
| M27856 | Lanopepden | Antibiotic |
| GSK 1322322 | ||
| Lanopepden (GSK 1322322) is a peptide deformylase inhibitor active against Staphylococcus aureus strains with MICs of 1 and 1 mg/L for ATCC 29213 and ATCC 25923 strain, respectively. | ||
| M42557 | PDE4-IN-14 | PDE |
| PDE4-IN-14 is a PDE4 inhibitor that can be used in the study of PDE4-related diseases (such as inflammatory and immune diseases, cancer, and metabolic diseases, etc.). | ||
| M42563 | PDE5-IN-10 | PDE |
| PDE5-IN-10 is a potent PDE5 inhibitor with an IC50 of 20 nM. | ||
| M42565 | PDE1-IN-5 | PDE |
| PDE1-IN-5 is a selective PDE1C inhibitor (IC50: 15 nM). | ||
| M42566 | PDE4-IN-13 | PDE |
| PDE4-IN-13 is a PDE4 inhibitor with an IC50 of 1.56 μM. | ||
| M50740 | Tapderimotide | Others |
| Tapderimotide (hTERT (691–705)) is an immunological agent for active immunization. | ||
| M54371 | Erepdekinra | IL Receptor/Related |
| Erepdekinra is an interleukin-17A (IL-17A) receptor antagonist. | ||
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