| Cat.No. | Name | Information |
|---|---|---|
| M10446 | 1400W dihydrochloride | 1400W dihydrochloride is a potent and selective inhibitor of human inducible NO synthase with Ki values of 7 nM. |
| M4390 | Imperatorin | Imperatorin is a potent NO synthesis inhibitor with an IC50 of 9.2 μmol and a BChE inhibitor with an IC50 of 31.4 μmol. Imperatorin is a weak agonist of TRPV1 with an EC50 of 12.6±3.2 μM. |
| M2357 | 2-Thiouracil | 2-Thiouracil is a thiolated uracil derivative that is a known antihyperthyroid agent. |
| M52846 | Camstatin | Camstatin, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase. |
| M52845 | N'-Nitro-D-arginine | N'-Nitro-D-arginine, a nitric oxide synthesis inhibitor, also is a vasodilator that relaxes the smooth muscles and increases blood flow to the penis, improving erections. |
| M44813 | Cis-N-Feruloyltyramine | N-cis-Feruloyl tyramine (cis-N-(4-Hydroxyphenethyl) ferulamide) is a natural phenolic compound, exhibits modest inhibitory activity on LPS-activated NO production in RAW 264.7 cells. |
| M44805 | Chloranthalactone E | Chloranthalactone E (compound 6), a labdane diterpene, can be isolated from the aerial parts of Chloranthus serratus. Chloranthalactone E inhibits NO production in LPS-activated RAW 264.7 macrophages. |
| M44782 | Apterin | Apterin is a natural compound with anti-inflammatory activity. Apterin shows significantly inhibitory activity on NO production in RAW264.7 cells with an IC50 value of 41.8 μM. |
| M42015 | Alismol | Alismol is a natural sesquiterpene. |
| M42014 | Anhydronotoptol | Anhydronotoptol is a potent nitric oxide inhibitory coumarin. |
| M42013 | hnNOS-IN-3 | hnNOS-IN-3 is a selective nNOS inhibitor, with a Ki of 0.32 μM. |
| M42012 | Vinyl-L-NIO hydrochloride | Vinyl-L-NIO hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. |
| M42011 | hnNOS-IN-2 | hnNOS-IN-2 is a human neuronal nitric oxide synthase (hnNOS) inhibitor with good metabolic stability. |
| M42010 | D-NAME hydrochloride | D-NAME (D-NG-nitroarginine methyl ester) hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. |
| M42009 | S-MTC dihydrochloride | S-MTC (S-Methyl-L-thiocitrulline) dihydrochloride is a selective type I nitric oxide synthase (NOS) inhibitor. |
| M42008 | L-NIO | L-NIO is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively. |
| M38996 | Kazinol B | Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research. |
| M38995 | Physalin O | Physalin O is a physalin that can be isolated from Physalis angulata. Physalin O shows cytotoxicity to Hep G2 and MCF-7 cancer cells with IC50 values of 31.1 and 11.4 µM, respectively. Physalin O inhibits the production of nitric oxide (NO) and shows anti-inflammatory activities. |
| M38993 | Cauloside D | Cauloside D is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside D exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines. |
| M38992 | Cauloside C | Cauloside C is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside C exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines. |
| M38991 | Myricananin A | Myricananin A is a colorless needle that has inhibitory effect on iNOS. |
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