All AbMole products are for research use only, cannot be used for human consumption.
Diphenyleneiodonium chloride (DPI) is an irreversible inhibitor of iNOS and eNOS with IC50 values of 50 nM and 0.3 µM, respectively. DPI chloride has been used to inhibit other flavoenzymes such as neutrophil NADPH oxidase and to bind strongly to flavoproteins. DPI chloride is thus a powerful and specific inhibitor of several important enzymes, including NADPH cytochrome P450 oxidoreductase, NADPH oxidases and NADPH-ubiquinone oxidoreductase.
| Molecular Weight | 314.55 |
| Formula | C12H8I.Cl |
| CAS Number | 4673-26-1 |
| Solubility (25°C) | DMSO 6 mg/mL (with warming) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related NO Synthase Products |
|---|
| L-Arginine-13C6,15N4 hydrochloride
L-Arginine-13C6,15N4 hydrochloride is the 13C- and 15N-labeled L-Arginine hydrochloride. |
| FeTPPS
FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process. FeTPPS possesses evident neuroprotective effects in a experimental model of spinal cord damage. |
| (S)-ZLc002
(S)-ZLc002 is a S-enantiomer of ZLc-002. |
| GW274150
GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM). |
| NOS-IN-1
NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
