NO Synthase Nitric oxide synthase (NOS)

Cat.No.	Name	Information
M10446	1400W dihydrochloride	1400W dihydrochloride is a potent and selective inhibitor of human inducible NO synthase with Ki values of 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex.
M14101	Syzalterin	Syzalterin is an inhibitor of NO production with an IC50 of 1.87 μg/mL.
M14100	L-NIO dihydrochloride	L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with K_is of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively.
M14099	L-NIL	L-NIL is an inducible NO synthase inhibitor, with an IC50 of 3.3 μM for miNOS.
M14098	GW274150 phosphate	GW274150 phosphate is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC₅₀=2.19 μM; K_d=40 nM) and rat iNOS (ED₅₀=1.15 μM).