NO Synthase Nitric oxide synthase (NOS)

Cat.No.	Name	Information
M10446	1400W dihydrochloride	1400W dihydrochloride is a potent and selective inhibitor of human inducible NO synthase with Ki values of 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex.
M56370	Nω-Propyl-L-arginine hydrochloride	Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM.
M56369	Mercaptoethylguanidine (MEG) (dihydrobromide)	Mercaptoethylguanidine (MEG) dihydrobromide is selective inhibitor of the inducible nitric oxide synthase and peroxynitrite scavenger.
M52846	Camstatin	Camstatin, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase.
M52845	N'-Nitro-D-arginine	N'-Nitro-D-arginine, a nitric oxide synthesis inhibitor, also is a vasodilator that relaxes the smooth muscles and increases blood flow to the penis, improving erections.
M44813	Cis-N-Feruloyltyramine	N-cis-Feruloyl tyramine (cis-N-(4-Hydroxyphenethyl) ferulamide) is a natural phenolic compound, exhibits modest inhibitory activity on LPS-activated NO production in RAW 264.7 cells.
M44805	Chloranthalactone E	Chloranthalactone E (compound 6), a labdane diterpene, can be isolated from the aerial parts of Chloranthus serratus. Chloranthalactone E inhibits NO production in LPS-activated RAW 264.7 macrophages.
M44782	Apterin	Apterin is a natural compound with anti-inflammatory activity. Apterin shows significantly inhibitory activity on NO production in RAW264.7 cells with an IC50 value of 41.8 μM.
M42015	Alismol	Alismol is a natural sesquiterpene.
M42014	Anhydronotoptol	Anhydronotoptol is a potent nitric oxide inhibitory coumarin.
M42013	hnNOS-IN-3	hnNOS-IN-3 is a selective nNOS inhibitor, with a Ki of 0.32 μM.
M42012	Vinyl-L-NIO hydrochloride	Vinyl-L-NIO hydrochloride is a potent nitric oxide synthase (NOS) inhibitor.
M42011	hnNOS-IN-2	hnNOS-IN-2 is a human neuronal nitric oxide synthase (hnNOS) inhibitor with good metabolic stability.
M42010	D-NAME hydrochloride	D-NAME (D-NG-nitroarginine methyl ester) hydrochloride is a potent nitric oxide synthase (NOS) inhibitor.
M42009	S-MTC dihydrochloride	S-MTC (S-Methyl-L-thiocitrulline) dihydrochloride is a selective type I nitric oxide synthase (NOS) inhibitor.
M42008	L-NIO	L-NIO is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively.
M38996	Kazinol B	Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research.
M38995	Physalin O	Physalin O is a physalin that can be isolated from Physalis angulata. Physalin O shows cytotoxicity to Hep G2 and MCF-7 cancer cells with IC50 values of 31.1 and 11.4 µM, respectively. Physalin O inhibits the production of nitric oxide (NO) and shows anti-inflammatory activities.
M38992	Cauloside C	Cauloside C is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside C exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines.
M38991	Myricananin A	Myricananin A is a colorless needle that has inhibitory effect on iNOS.
M38990	Longiferone B	Longiferone B is a daucane sesquiterpene, that can be isolated from Boesenbergia longiflora rhizomes. Longiferone B shows anti-inflammatory activity against NO release with an IC50 of 21.0 μM. Longiferone B also suppresses the iNOS and COX-2 mRNA expression.

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NO Synthase Nitric oxide synthase (NOS)

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