| Cat.No. | Name | Information |
|---|---|---|
| M4552 | Nobiletin | Nobiletin is a citrus flavonoid with anti-inflammatory, anti-cancer, cholesterol lowering, memory protection activities. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes. |
| M4551 | Trigonelline hydrochloride | Trigonelline chloride is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline chloride is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. |
| M4550 | Maslinic-acid | Maslinic-acid (MA) is a natural triterpenoid with a wide range of biological activities, such as anti-tumor, anti-diabetes, antioxidant, heart-protective, neuroprotective, anti-parasitic and growth stimulating, Maslinic acid inhibited THE DNA binding activity of NF-κB P65 and eliminated the PHOSPHORylation of IκB-α. |
| M4549 | Glucosyl-vitexin | 4 "-O-glucosylvitexin is a bioactive flavonoid extracted from hawthorn leaves. |
| M4548 | Vitexin | Vitexin is a C-glycosylated flavonoid found in a variety of medicinal plants such as Ficus deltoid and Spirulina (Spirodela polyrhiza). Vitexin has a wide range of pharmacological effects, including antioxidant, anticancer, anti-inflammatory, anti-hyperalgesia and neuroprotective effects. |
| M4547 | Roburic-acid | Roburic acid is a tetracyclic triterpenoid in Gentiana macrophylla. As an inhibitor of COX, the IC50 values of COX-1 and COX-2 are 5 and 9 μM, respectively. |
| M4546 | Loganic-acid | Loganic acid is a type of iridoid isolated from the fruit of dogwood. Loganic acid regulates diet-related atherosclerosis and REDOX states. Loganic acid has strong free radical scavenging activity and significant cellular protection against heavy metal-mediated toxicity. |
| M4545 | Isorhamnetin-3-O-neohespeidoside | Isorhamnetin-3-o-neohespeidoside is a flavonoid isolated from Pollen typhae. |
| M4544 | Typhaneoside | Typhaneoside, extracted from Typha Angustifolia L., inhibits autophagy in hypoxia/reoxygenation cells and increases the phosphorylation of Akt and mTOR. Typhaneoside has certain effects on the cardiovascular system, including lowering lipid levels, promoting anti-atherosclerotic activity, and improving immune and clotting function. |
| M4543 | Byakangelicin | (Rac)-Byakangelicin is the racemate of Byakangelicin, which is mainly separated from the genus Angelica. Byakangelicin is an aldose reductase inhibitor with an IC50 value of 6.2 μM. |
| M4542 | Neoandrographolide | Neoandrographolide is a diterpenoid compound isolated from Andrographolide. |
| M4541 | Dehydroandrographolide | Dehydroandrographolide is extracted from the herb andrographolia andrographolide. Dehydroandrographolide reduces oxidative stress in LPS-induced acute lung injury by inactivating iNOS and has anti-infective activity. |
| M4540 | Scutellarein | Scutellarein is a natural flavonoid with anti-inflammatory effects. |
| M4539 | Polygalasaponin-F | Polygalasaponin F is an oleanane type triterpenoid saponin extracted from Polygala Japonica, which can reduce the release of inflammatory cytokine tumor necrosis factor α (TNFa). Polygalasaponin F reduces the secretion of neuroinflammatory cytokines by regulating the TLR4-PI3K/ Akt-NF-KB signaling pathway. |
| M4536 | Myricetrin | Myricitrin is a major antioxidant. |
| M4535 | Myricetin | Myricetin is a platelet activating factor (PAF) antagonist. |
| M4534 | Daurisoline | Daurisoline is an hERG inhibitor and also an autophagy inhibitor. |
| M4533 | Dauricine | Dauricine is a diphenylisoquinoline alkaloid isolated from Asiatic Moonseed Rhizome and has anti-inflammatory activity. Dauricine inhibited proliferation, invasion and apoptosis of colon cancer cells in a dose-dependent manner by inhibiting NF-κB activation. |
| M4532 | Rhodionin | Rhodionin was isolated from the roots of Rhodiola crenulata and is a specific non-competitive cytochrome P450 2D6 inhibitor with IC50 of 0.761 μM and Ki of 0.769 μM. Rhodionin effectively inhibited acetylcholinesterase (AChE) in a dose-dependent manner with an IC50 range of 57.50 to 2.43 μg/mL. Rhodionin had effective DPPH radical scavenging activity with IC50 of 19.49 μM. |
| M4531 | Rosiridin | Rosiridin inhibits MAO A and MAO B and has A potential role in depression and alzheimer's disease. The inhibition rate of Rosiridin against MAO B at 10 μM was 83.8% (pIC50=5.38). |
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