| Cat.No. | Name | Information |
|---|---|---|
| M4573 | Diosmetin | Diosmetin is a natural flavonoid that inhibits the activity of human CYP1A enzyme. The IC50 value of Diosmetin in HepG2 cells is 40 μM. |
| M4572 | Limonin | Limonin is a potent inhibitor of CYP3A4 with an IC50 of 6.2 μM. Limonin inhibits HIV-1 with an EC50 of 60.0 μM. Limonin induces human colon adenocarcinoma cells apoptosis with an IC50 of 54.74 μM. Limonin, a triterpenoid rich in citrus fruits, has antiviral and anti-tumor activities. |
| M4571 | Neohesperidin | Neohesperidin is an antioxidant agent with an IC50 of 22.31 μg/ml in the 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay. |
| M4570 | Palmatine | Palmatine is an orally active and irreversible IDO-1 inhibitor. Palmatine ameliorates colitis induced by Dextran Sulphate Sodium Salt (DSS) by reducing colon injury, preventing intestinal microbiome imbalance and regulating tryptophan catabolism. Palmatine has potential for colitis research. |
| M4569 | AescinIIB | Escin IIb, isolated from horse chestnut seed horse chestnut, has a positive effect on acute inflammation in animals. Escin IIb has a significant protective effect on gastric mucosa injury induced by ethanol. |
| M4568 | Aescin-IIA | Escin IIa, isolated from horse chestnut seed horse chestnut, has a positive effect on acute inflammation in animals. Escin IIa has obvious protective effect on gastric mucosa injury induced by ethanol. |
| M4567 | Escin-IB | Escin IB is a saponin isolated from the skin and endosperm of horse chestnut (Aesculus hippocastanum) seeds. Escin IB has an inhibitory effect on pancreatic lipase activity. |
| M4566 | Escin-IA | Escin IA, a triterpenoid saponin isolated from horse chestnut, inhibits HIV-1 protease with IC50 value of 35 μM. Escin IA has anti-metastasis activity of triple negative breast cancer, and its mechanism includes down-regulation of LOXL expression and inhibition of epithelial mesenchymal transformation. |
| M4565 | (-)-Sparteine-sulfate-pentahydrate | (-)-Sparteine-sulfate-pentahydrate |
| M4564 | Lobetyolin | Lobetyolin is a bioactive compound isolated from Codonopsis Pilosula. Lobetyolin has anti-inflammatory, antioxidant and xanthine oxidase inhibitory activities. Lobetyolin also induces apoptosis by inhibiting ASCT2-mediated glutamine metabolism. |
| M4561 | Sodium-Demethylcantharidate | Sodium Demethylcantharidate is an endogenous metabolite. Sodium Demethylcantharidate induces apoptosis in hepatocellular carcinoma cells via ER stress, it shows excellent anticancer activity against multiple types of cancer. |
| M4560 | Paeonolide | Paeonolide is a plant glycoside containing a non-reducing terminal α -1-arabopyranoside, which is present in the roots of a wide range of plants of the Genus Paeonia. |
| M4559 | Ziyuglycoside-II | Ziyuglycoside II from Sanguisorba officinalis L. Triterpenoid saponins extracted from the. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. It has anti-inflammatory and anticancer effects. |
| M4558 | Ziyuglycoside-I | Ziyuglycoside I, isolated from S. officinalis root, has anti-wrinkle activity and increases type I collagen expression. Ziyuglycoside I can be used as an active ingredient in cosmetics. Ziyuglycoside I can induce p53-mediated cell cycle arrest and apoptosis, which can be used in the study of triple negative breast cancer. |
| M4557 | Dictamine | Dictamnine (Dictamine) is cytotoxic to human cervical and colon cancer cells, and also has antibacterial and antifungal activities. |
| M4556 | Fraxinellone | Fraxinellone was isolated from the root bark of the brassica family Dictamnus dasycarpus. Fraxinellone is a PD-L1 inhibitor that inhibits HIF-1α synthesis without affecting HIF-1α degradation. Fraxinellone has potential for cancer immunity by targeting PD-L1. |
| M4555 | Cyanidin chloride | Cyanidin chloride is a subclass of anthocyanin, displays antioxidant and anti-carcinogenesis properties, could be used for treatment of diabetes mellitus complications. |
| M4554 | Cyanidin-3-O-glucoside | Kuromanin 3-O-glucoside (Kuromanin chloride), derived from mulberry leaves, has the effect of increasing blood glucose concentration and maintaining lipid metabolism balance to reduce obesity. |
| M4553 | Tangeretin | Tangeretin is a flavonoid from citrus fruit peels, and is also selected as a Notch-1 inhibitor, which plays an important role in anti-inflammatory responses and neuroprotective effects in several disease models. |
| M4552 | Nobiletin | Nobiletin is a citrus flavonoid with anti-inflammatory, anti-cancer, cholesterol lowering, memory protection activities. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes. |
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