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Esculentoside A (EsA), A triterpenoid saponin isolated from the root of Phytolacca esculenta. Esculentoside A (EsA) showed anti-inflammatory activity and selective inhibition of cycde-2 (COX-2). Esculentoside A (EsA) inhibits inflammatory responses in LPS-induced acute lung injury (ALI) by inhibiting (NF- κ B) and mitogen-activated protein kinase (MAPK) signaling pathways.
| Molecular Weight | 826.96 |
| Formula | C42H66O16 |
| CAS Number | 65497-07-6 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related COX Products |
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| Sudoxicam
Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory agent from the enol-carboxamide class. |
| Metyrosine
Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine significantly inhibits high COX-2 activity. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. |
| PPOH
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. |
| Tenidap
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| COX-2-IN-6
COX-2-IN-6 is an orally active, gut-restricted and selective cyclooxygenase-2 (COX-2) inhibitor for colorectal Chemoprevention of cancer. |
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