| Cat.No. | Name | Information |
|---|---|---|
| M4595 | Isosilybin | Isosilybin (Isosilybinin) is a flavonoid from milk thistle; The IC50 value induced by CYP3A4 inhibition was 74 μM. |
| M4594 | Cytisine | Cytisinicline (Cytisine) is an alkaloid that can be extracted from Laburnum and Cytisus. Cytisinicline (Cytisine) is a partial agonist of α4β2 nicotinic acetylcholinergic receptors (α4β2 nAChRs), and also a partial agonist of α4β2 and α7 receptors. It has been used medically to help people quit smoking. |
| M4593 | Yohimbine-Hydrochloride | Yohimbine hydrochloride is an α2-adrenergic receptor antagonist. |
| M4592 | Xylitol | Xylitol can be classified as polyols and sugar alcohols. |
| M4591 | Sodium-Aescinate | Sodium Aescinate is a triterpenoid saponin from Aesculus hippocastanum seeds with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits liver cancer growth by targeting the CARMA3/NF-κB pathway. |
| M4590 | Buddleoside | Buddleoside |
| M4589 | Luteolin | Luteolin (Luteoline) is a flavanoid that can induce cell apoptosis and cell cycle arrest in several cancer cell lines. Luteolin (Luteoline) is also a potent Nrf2 inhibitor. |
| M4588 | Astilbin | Astilbin is a flavonoid that enhances NRF2 activation. Astilbin also inhibited TNF-α expression and NF-κB activation. |
| M4587 | β-Carotene | Beta-carotene (Provitamin A) is A class of carotenoid compounds that are naturally occurring precursors of vitamin A. Beta-carotene is a ROS regulator with antioxidant and anti-inflammatory activities. β -carotene can be either an antioxidant or a pro-oxidant, depending on its intrinsic properties and the REDOX potential of the biological environment it acts on. β -carotene can induce apoptosis of breast cancer cells and has anti-cancer activity. |
| M4585 | Taxifolin (TFN) | Taxifolin (TFN) is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity. Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. |
| M4584 | Acacetin | Acacetin is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects. |
| M4583 | (-)-Maackiain | Maackiain (DL-Maackiain) was separated from Maackia amurensis Rupr. Et Maxim. Maackiain (DL-Maackiain) is a larval insecticide against Aedes aegypti with a LD50 of 21.95 μg/ mL. Maackiain (DL-Maackiain) induces DNA fragmentation into oligonucleosome size fragments, similar to apoptotic characteristics such as HL-60 cells. |
| M4582 | Germacrone | Germacrone is derived from turmeric and inhibits influenza virus infection. |
| M4581 | Dihydrocurcumin | Dihydrocurcumin |
| M4580 | Cyclovirobuxine | Cyclovirobuxine D (CVB-D) is the main active ingredient of Buxus microphylla. Cyclovirobuxine D induces autophagy and reduces Akt and mTOR phosphorylation. Cyclovirobuxine D inhibits the proliferation of cancer cells by inhibiting cell cycle progression and inducing mitochondria - mediated apoptosis. Cyclovirobuxine D has the potential to be used in the study of heart failure caused by myocardial infarction. |
| M4579 | Syringin | Syringin is one of the main bioactive phenolic glycosides in Acanthopanax senticosus and has anti-osteoporosis effect. Syringin prevents cardiac hypertrophy caused by pressure overload by inhibiting autophagy. |
| M4578 | Oridonin | Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity. Oridonin (NSC-250682) also acts as an inhibitor of AKT, with IC50 values of 8.4 and 8.9 μM for AKT1 and AKT2, respectively. |
| M4576 | Segetalin-A | Segetalin-A |
| M4575 | Vaccarin | Vaccarin is an active flavonoid glycoside with a variety of biological functions. Vaccarin significantly promoted wound healing and proliferation of endothelial and fibroblast cells at the wound site. Vaccarin improves insulin resistance and steatosis by activating the AMPK signaling pathway. |
| M4574 | Wedelolactone | Wedelolactone, a medicinal plant-derived natural compound, is an inhibitor of IKK that is critical for activation of NF-κB by mediating phosphorylation and degradation of IκBα. Wedelolactone is also an inhibitor of caspase-11. |
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