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Crotonoside

Cat. No. M4646

All AbMole products are for research use only, cannot be used for human consumption.

Crotonoside Structure
Size Price Availability Quantity
20mg USD 170  USD170 In stock
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Quality Control & Documentation
Biological Activity

Crotonoside is isolated from Chinese medicinal herb, Croton. Crotonoside inhibits FLT3 and HDAC3/6, exhibits selective inhibition in acute myeloid leukemia (AML) cells. Crotonoside could be a promising new lead compound for the treatment of AML.

Chemical Information
Molecular Weight 283.24
Formula C10H13N5O5
CAS Number 1818-71-9
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fhatuwani Thovhogi, et al. Evaluation of Leaf Mineral, Flavonoid, and Total Phenolic Content in Spider Plant Germplasm

[2] Shih-Chao Lin, et al. Alleviation of Collagen-Induced Arthritis by Crotonoside through Modulation of Dendritic Cell Differentiation and Activation

[3] Zhipei Liu, et al. Antiarrhythmic effect of crotonoside by regulating sodium and calcium channels in rabbit ventricular myocytes

[4] Yu-Zhi Li, et al. Crotonoside exhibits selective post-inhibition effect in AML cells via inhibition of FLT3 and HDAC3/6

[5] Peiao Yan, et al. Pharmacokinetics and tissue distribution of crotonoside

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Keywords: Crotonoside supplier, FLT3, inhibitors, activators

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