|M10181||STK321130||STK321130, also known as FLT3-IN-2, is potent FLT3 inhibitor with IC50 of <1 μM.|
|M7527||Gilteritinib||Gilteritinib is a potent FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively.|
|M5311||AMG 925||AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.|
|M5142||G-749||G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.|
|M5026||UNC-2025||UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.|
|M3800||CGP52421||CGP52421 is a FLT3 inhibitor, which is also an metabolite of midostaurin (PKC412).|
|M3053||TCS 359||TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.|
|M1828||Tandutinib||Tandutinib (MLN518), previously known as CT53518, is an orally active multitargeted tyrosine kinase inhibitor of FLT3, PDGFR and c-Kit.|
|M1815||KW-2449||KW-2449 is a novel multitargeted kinase inhibitor of FLT3, ABL and Aurora kinase with IC50 values of 6.6 nM, 14 nM and 48 nM.|
|M1641||AC220||AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor.|
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